Inhibition of glycolysis and stimulation of mitochondrial biogenesis lead to increased ROS levels and cell death in HNF-1ß positive clear cell carcinoma.
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| Title: | Inhibition of glycolysis and stimulation of mitochondrial biogenesis lead to increased ROS levels and cell death in HNF-1ß positive clear cell carcinoma. |
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| Authors: | Kawahara N; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan. naoki35@naramed-u.ac.jp., Kuniyasu H; Department of Molecular Pathology, Nara Medical University, Kashihara, Japan. cooninh@zb4.so-net.ne.jp., Mori S; Department of Molecular Pathology, Nara Medical University, Kashihara, Japan.; Department of Cancer Biology, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan., Kishi S; Department of Pathology, Kansai Medical University, Hirakata, Osaka, Japan., Sugimoto S; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan., Maehana T; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan., Yamanaka S; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan., Kawaguchi R; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan., Kimura F; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan. |
| Source: | Cell death & disease [Cell Death Dis] 2025 Dec 01; Vol. 16 (1), pp. 879. Date of Electronic Publication: 2025 Dec 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-4889 |
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| DOI: | 10.1038/s41419-025-08243-2 |
