Inhibition of glycolysis and stimulation of mitochondrial biogenesis lead to increased ROS levels and cell death in HNF-1ß positive clear cell carcinoma.
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| Title: | Inhibition of glycolysis and stimulation of mitochondrial biogenesis lead to increased ROS levels and cell death in HNF-1ß positive clear cell carcinoma. |
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| Authors: | Kawahara N; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan. naoki35@naramed-u.ac.jp., Kuniyasu H; Department of Molecular Pathology, Nara Medical University, Kashihara, Japan. cooninh@zb4.so-net.ne.jp., Mori S; Department of Molecular Pathology, Nara Medical University, Kashihara, Japan.; Department of Cancer Biology, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan., Kishi S; Department of Pathology, Kansai Medical University, Hirakata, Osaka, Japan., Sugimoto S; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan., Maehana T; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan., Yamanaka S; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan., Kawaguchi R; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan., Kimura F; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan. |
| Source: | Cell death & disease [Cell Death Dis] 2025 Dec 01; Vol. 16 (1), pp. 879. Date of Electronic Publication: 2025 Dec 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41326368 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Inhibition of glycolysis and stimulation of mitochondrial biogenesis lead to increased ROS levels and cell death in HNF-1ß positive clear cell carcinoma. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Kawahara+N%22">Kawahara N</searchLink>; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan. naoki35@naramed-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Kuniyasu+H%22">Kuniyasu H</searchLink>; Department of Molecular Pathology, Nara Medical University, Kashihara, Japan. cooninh@zb4.so-net.ne.jp.<br /><searchLink fieldCode="AU" term="%22Mori+S%22">Mori S</searchLink>; Department of Molecular Pathology, Nara Medical University, Kashihara, Japan.; Department of Cancer Biology, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan.<br /><searchLink fieldCode="AU" term="%22Kishi+S%22">Kishi S</searchLink>; Department of Pathology, Kansai Medical University, Hirakata, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Sugimoto+S%22">Sugimoto S</searchLink>; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan.<br /><searchLink fieldCode="AU" term="%22Maehana+T%22">Maehana T</searchLink>; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan.<br /><searchLink fieldCode="AU" term="%22Yamanaka+S%22">Yamanaka S</searchLink>; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan.<br /><searchLink fieldCode="AU" term="%22Kawaguchi+R%22">Kawaguchi R</searchLink>; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan.<br /><searchLink fieldCode="AU" term="%22Kimura+F%22">Kimura F</searchLink>; Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2025 Dec 01; Vol. 16 (1), pp. 879. <i>Date of Electronic Publication: </i>2025 Dec 01. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41326368 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41419-025-08243-2 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 879 Titles: – TitleFull: Inhibition of glycolysis and stimulation of mitochondrial biogenesis lead to increased ROS levels and cell death in HNF-1ß positive clear cell carcinoma. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kawahara N – PersonEntity: Name: NameFull: Kuniyasu H – PersonEntity: Name: NameFull: Mori S – PersonEntity: Name: NameFull: Kishi S – PersonEntity: Name: NameFull: Sugimoto S – PersonEntity: Name: NameFull: Maehana T – PersonEntity: Name: NameFull: Yamanaka S – PersonEntity: Name: NameFull: Kawaguchi R – PersonEntity: Name: NameFull: Kimura F IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: 2025 Dec 01 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2041-4889 Numbering: – Type: volume Value: 16 – Type: issue Value: 1 Titles: – TitleFull: Cell death & disease Type: main |
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