Characterization of the safety profile of trastuzumab deruxtecan by dose: a pooled analysis across DESTINY studies.

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Title: Characterization of the safety profile of trastuzumab deruxtecan by dose: a pooled analysis across DESTINY studies.
Authors: Park YH; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea., Cortes J; Oncology Department, International Breast Cancer Center (IBCC), Pangaea Oncology, Quiron Group, Barcelona, Spain.; IOB Madrid, Institute of Oncology, Hospital Beata María Ana, Madrid, Spain.; Oncology Department, Hospital Universitario Torrejón, Ribera Group, Madrid, Spain.; Department of Medicine, Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Madrid, Spain.; Medica Scientia Innovation Research (MEDSIR) - Oncoclínicas&Co, Jersey City, NJ, United States., Modi S; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States., Hurvitz SA; Division of Hematology and Oncology and Clinical Research Division, Department of Medicine, UW Medicine, Fred Hutchinson Cancer Center, Seattle, WA, United States., Bianchini G; Department of Medical Oncology, IRCCS Ospedale San Raffaele and Università Vita-Salute San Raffaele, Milan, Italy., Iwata H; Breast Oncology Department, Aichi Cancer Center Hospital, Nagoya, Japan., Shitara K; Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan., Siena S; Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Department of Hematology, Oncology, and Molecular Medicine, Niguarda Cancer Center, and Grande Ospedale Metropolitano Niguarda, Milan, Italy., Goto Y; Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan., Ku GY; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States., Powell CA; Division of Pulmonary, Critical Care and Sleep Medicine, Tisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Swain SM; Georgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center and Genetic Medicine, MedStar Health, Washington DC, United States., Arunachalam M; Daiichi Sankyo, Inc., Basking Ridge, NJ, United States., Janek M; Daiichi Sankyo, Inc., Basking Ridge, NJ, United States., Cheng Y; Daiichi Sankyo, Inc., Basking Ridge, NJ, United States., Chu C; Daiichi Sankyo, Inc., Basking Ridge, NJ, United States., Verma P; Daiichi Sankyo, Inc., Basking Ridge, NJ, United States., Kuptsova-Clarkson N; Patient Safety, Oncology, AstraZeneca, Gaithersburg, MD, United States., Mathias E; Daiichi Sankyo, Inc., Basking Ridge, NJ, United States., Goodman E; Daiichi Sankyo, Inc., Basking Ridge, NJ, United States., Rugo HS; Department of Medicine, University of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, United States.
Source: The oncologist [Oncologist] 2025 Dec 27; Vol. 31 (1).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9607837 Publication Model: Print Cited Medium: Internet ISSN: 1549-490X (Electronic) Linking ISSN: 10837159 NLM ISO Abbreviation: Oncologist Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1549-490X
DOI:10.1093/oncolo/oyaf396