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High Torque teno virus viremia predicts long-term mortality and reflects chronic low-grade inflammation (inflammaging) in geriatric inpatients.

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Title: High Torque teno virus viremia predicts long-term mortality and reflects chronic low-grade inflammation (inflammaging) in geriatric inpatients.
Authors: Cianfruglia L; Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy., Badillo Pazmay GV; Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy., Fortunato C; Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy., Spezia PG; Laboratory of Virology, National Institute for Infectious Diseases, Lazzaro Spallanzani- IRCCS, Rome, Italy., Novazzi F; Department of Medicine and Technological innovation, University of Insubria, Varese, Italy; Laboratory of Microbiology, ASST Sette Laghi, Varese, Italy., Piacenza F; Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy., Malavolta M; Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy; Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy., Marchegiani F; Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy., Recchioni R; Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy., Matacchione G; Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy., Giordani C; Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy., Cardelli M; Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy., Casoli T; Center for Neurobiology of Aging, IRCCS INRCA, Ancona, Italy., Di Rosa M; Centre for Biostatistics and Applied Geriatric Clinical Epidemiology, IRCCS INRCA, Ancona, Italy., Cherubini A; Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy; Geriatria, Accettazione Geriatrica e Centro di ricerca per l'invecchiamento, IRCCS INRCA, Ancona, Italy., Pelliccioni G; Neurology Unit, IRCCS INRCA, Ancona, Italy., Sarzani R; Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy; Internal Medicine and Geriatrics, 'Hypertension Excellence Centre' of the European Society of Hypertension, Società Italiana per lo Studio dell'Aterosclerosi (SISA) LIPIGEN Centre, IRCCS INRCA, Ancona, Italy., Spannella F; Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy; Internal Medicine and Geriatrics, 'Hypertension Excellence Centre' of the European Society of Hypertension, Società Italiana per lo Studio dell'Aterosclerosi (SISA) LIPIGEN Centre, IRCCS INRCA, Ancona, Italy., Lattanzio F; Scientific Direction, IRCCS INRCA, Ancona, Italy., Bonfigli AR; Scientific Direction, IRCCS INRCA, Ancona, Italy., Olivieri F; Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy; Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy., Sabbatinelli J; Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy; Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy., Maggi F; Laboratory of Virology, National Institute for Infectious Diseases, Lazzaro Spallanzani- IRCCS, Rome, Italy., Giacconi R; Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy. Electronic address: r.giacconi@inrca.it.
Source: Experimental gerontology [Exp Gerontol] 2026 Jan; Vol. 213, pp. 112978. Date of Electronic Publication: 2025 Dec 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0047061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6815 (Electronic) Linking ISSN: 05315565 NLM ISO Abbreviation: Exp Gerontol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: High Torque teno virus viremia predicts long-term mortality and reflects chronic low-grade inflammation (inflammaging) in geriatric inpatients.
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  Data: <searchLink fieldCode="AU" term="%22Cianfruglia+L%22">Cianfruglia L</searchLink>; Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Badillo+Pazmay+GV%22">Badillo Pazmay GV</searchLink>; Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Fortunato+C%22">Fortunato C</searchLink>; Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Spezia+PG%22">Spezia PG</searchLink>; Laboratory of Virology, National Institute for Infectious Diseases, Lazzaro Spallanzani- IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Novazzi+F%22">Novazzi F</searchLink>; Department of Medicine and Technological innovation, University of Insubria, Varese, Italy; Laboratory of Microbiology, ASST Sette Laghi, Varese, Italy.<br /><searchLink fieldCode="AU" term="%22Piacenza+F%22">Piacenza F</searchLink>; Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Malavolta+M%22">Malavolta M</searchLink>; Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy; Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Marchegiani+F%22">Marchegiani F</searchLink>; Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Recchioni+R%22">Recchioni R</searchLink>; Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Matacchione+G%22">Matacchione G</searchLink>; Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Giordani+C%22">Giordani C</searchLink>; Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Cardelli+M%22">Cardelli M</searchLink>; Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Casoli+T%22">Casoli T</searchLink>; Center for Neurobiology of Aging, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Rosa+M%22">Di Rosa M</searchLink>; Centre for Biostatistics and Applied Geriatric Clinical Epidemiology, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Cherubini+A%22">Cherubini A</searchLink>; Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy; Geriatria, Accettazione Geriatrica e Centro di ricerca per l'invecchiamento, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Pelliccioni+G%22">Pelliccioni G</searchLink>; Neurology Unit, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Sarzani+R%22">Sarzani R</searchLink>; Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy; Internal Medicine and Geriatrics, 'Hypertension Excellence Centre' of the European Society of Hypertension, Società Italiana per lo Studio dell'Aterosclerosi (SISA) LIPIGEN Centre, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Spannella+F%22">Spannella F</searchLink>; Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy; Internal Medicine and Geriatrics, 'Hypertension Excellence Centre' of the European Society of Hypertension, Società Italiana per lo Studio dell'Aterosclerosi (SISA) LIPIGEN Centre, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Lattanzio+F%22">Lattanzio F</searchLink>; Scientific Direction, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Bonfigli+AR%22">Bonfigli AR</searchLink>; Scientific Direction, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Olivieri+F%22">Olivieri F</searchLink>; Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy; Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Sabbatinelli+J%22">Sabbatinelli J</searchLink>; Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy; Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Maggi+F%22">Maggi F</searchLink>; Laboratory of Virology, National Institute for Infectious Diseases, Lazzaro Spallanzani- IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Giacconi+R%22">Giacconi R</searchLink>; Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy. Electronic address: r.giacconi@inrca.it.
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  Data: <searchLink fieldCode="JN" term="%220047061%22">Experimental gerontology</searchLink> [Exp Gerontol] 2026 Jan; Vol. 213, pp. 112978. <i>Date of Electronic Publication: </i>2025 Dec 01.
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