The specificity and structure of DNA cross-linking by the gut bacterial genotoxin colibactin.
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| Title: | The specificity and structure of DNA cross-linking by the gut bacterial genotoxin colibactin. |
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| Authors: | Carlson ES; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA., Haslecker R; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA., Lecchi C; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Aguilar Ramos MA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA., Vennelakanti V; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Honaker L; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA., Stornetta A; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Millán ES; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA., Johnson BA; Structural Biology Initiative, City University of New York (CUNY) Advanced Science Research Center, New York, NY, USA., Kulik HJ; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Balbo S; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Villalta PW; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, MN, USA., D'Souza VM; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA., Balskus EP; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.; Howard Hughes Medical Institute, Harvard University, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. |
| Source: | Science (New York, N.Y.) [Science] 2025 Dec 04; Vol. 390 (6777), pp. eady3571. Date of Electronic Publication: 2025 Dec 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1095-9203 |
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| DOI: | 10.1126/science.ady3571 |
