Phase 1 Study of [177Lu]Lu-NeoB in Patients with Advanced Solid Tumors Overexpressing Gastrin-Releasing Peptide Receptor: Preliminary Safety and Dosimetry Results.
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| Title: | Phase 1 Study of [177Lu]Lu-NeoB in Patients with Advanced Solid Tumors Overexpressing Gastrin-Releasing Peptide Receptor: Preliminary Safety and Dosimetry Results. |
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| Authors: | Mittra ES; Division of Molecular Imaging and Therapy, Department of Radiology, Oregon Health & Science University, Portland, Oregon; mittra@ohsu.edu., Solnes LB; Division of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland., van der Veldt AAM; Department of Radiology and Nuclear Medicine and Department Medical Oncology, Erasmus Medical Center, Rotterdam, The Netherlands., Wong J; Department of Radiation Oncology, City of Hope National Cancer Center, Duarte, California., Aloj L; Department of Radiology, University of Cambridge, Cambridge, United Kingdom., Heinrich MC; Division of Hematology and Medical Oncology, Portland VA Health Care System and Oregon Health & Science University, Portland, Oregon., Chen CT; Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, California., Rowe SP; Molecular Imaging and Therapeutics, Department of Radiology, University of North Carolina, Chapel Hill, North Carolina., Brabander T; Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Pacey S; Department of Oncology, Clinical School, University of Cambridge, Cambridge, United Kingdom., Aimone P; Novartis Pharma AG, Basel, Switzerland., Pathak D; Novartis Pharma AG, Basel, Switzerland., Blumenstein L; Novartis Biomedical Research, Basel, Switzerland., Liu Y; Novartis Pharma Co., Ltd., Beijing, China; and., Iagaru A; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Stanford University, Stanford, California. |
| Source: | Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2026 Feb 02; Vol. 67 (2), pp. 262-268. Date of Electronic Publication: 2026 Feb 02. |
| Publication Type: | Journal Article; Clinical Trial, Phase I; Multicenter Study; Clinical Trial, Phase II; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1535-5667 |
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| DOI: | 10.2967/jnumed.125.270411 |
