Phase 1 Study of [177Lu]Lu-NeoB in Patients with Advanced Solid Tumors Overexpressing Gastrin-Releasing Peptide Receptor: Preliminary Safety and Dosimetry Results.
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| Title: | Phase 1 Study of [177Lu]Lu-NeoB in Patients with Advanced Solid Tumors Overexpressing Gastrin-Releasing Peptide Receptor: Preliminary Safety and Dosimetry Results. |
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| Authors: | Mittra ES; Division of Molecular Imaging and Therapy, Department of Radiology, Oregon Health & Science University, Portland, Oregon; mittra@ohsu.edu., Solnes LB; Division of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland., van der Veldt AAM; Department of Radiology and Nuclear Medicine and Department Medical Oncology, Erasmus Medical Center, Rotterdam, The Netherlands., Wong J; Department of Radiation Oncology, City of Hope National Cancer Center, Duarte, California., Aloj L; Department of Radiology, University of Cambridge, Cambridge, United Kingdom., Heinrich MC; Division of Hematology and Medical Oncology, Portland VA Health Care System and Oregon Health & Science University, Portland, Oregon., Chen CT; Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, California., Rowe SP; Molecular Imaging and Therapeutics, Department of Radiology, University of North Carolina, Chapel Hill, North Carolina., Brabander T; Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Pacey S; Department of Oncology, Clinical School, University of Cambridge, Cambridge, United Kingdom., Aimone P; Novartis Pharma AG, Basel, Switzerland., Pathak D; Novartis Pharma AG, Basel, Switzerland., Blumenstein L; Novartis Biomedical Research, Basel, Switzerland., Liu Y; Novartis Pharma Co., Ltd., Beijing, China; and., Iagaru A; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Stanford University, Stanford, California. |
| Source: | Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2026 Feb 02; Vol. 67 (2), pp. 262-268. Date of Electronic Publication: 2026 Feb 02. |
| Publication Type: | Journal Article; Clinical Trial, Phase I; Multicenter Study; Clinical Trial, Phase II; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41344852 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Phase 1 Study of [<superscript>177</superscript>Lu]Lu-NeoB in Patients with Advanced Solid Tumors Overexpressing Gastrin-Releasing Peptide Receptor: Preliminary Safety and Dosimetry Results. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Mittra+ES%22">Mittra ES</searchLink>; Division of Molecular Imaging and Therapy, Department of Radiology, Oregon Health & Science University, Portland, Oregon; mittra@ohsu.edu.<br /><searchLink fieldCode="AU" term="%22Solnes+LB%22">Solnes LB</searchLink>; Division of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22van+der+Veldt+AAM%22">van der Veldt AAM</searchLink>; Department of Radiology and Nuclear Medicine and Department Medical Oncology, Erasmus Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Wong+J%22">Wong J</searchLink>; Department of Radiation Oncology, City of Hope National Cancer Center, Duarte, California.<br /><searchLink fieldCode="AU" term="%22Aloj+L%22">Aloj L</searchLink>; Department of Radiology, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Heinrich+MC%22">Heinrich MC</searchLink>; Division of Hematology and Medical Oncology, Portland VA Health Care System and Oregon Health & Science University, Portland, Oregon.<br /><searchLink fieldCode="AU" term="%22Chen+CT%22">Chen CT</searchLink>; Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, California.<br /><searchLink fieldCode="AU" term="%22Rowe+SP%22">Rowe SP</searchLink>; Molecular Imaging and Therapeutics, Department of Radiology, University of North Carolina, Chapel Hill, North Carolina.<br /><searchLink fieldCode="AU" term="%22Brabander+T%22">Brabander T</searchLink>; Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Pacey+S%22">Pacey S</searchLink>; Department of Oncology, Clinical School, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Aimone+P%22">Aimone P</searchLink>; Novartis Pharma AG, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pathak+D%22">Pathak D</searchLink>; Novartis Pharma AG, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Blumenstein+L%22">Blumenstein L</searchLink>; Novartis Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Novartis Pharma Co., Ltd., Beijing, China; and.<br /><searchLink fieldCode="AU" term="%22Iagaru+A%22">Iagaru A</searchLink>; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Stanford University, Stanford, California. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220217410%22">Journal of nuclear medicine : official publication, Society of Nuclear Medicine</searchLink> [J Nucl Med] 2026 Feb 02; Vol. 67 (2), pp. 262-268. <i>Date of Electronic Publication: </i>2026 Feb 02. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Clinical Trial, Phase I; Multicenter Study; Clinical Trial, Phase II; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Society+of+Nuclear+Medicine%22">Society of Nuclear Medicine </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0217410 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1535-5667 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201615505%22">01615505 </searchLink><i>NLM ISO Abbreviation: </i>J Nucl Med <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41344852 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.2967/jnumed.125.270411 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 262 Titles: – TitleFull: Phase 1 Study of [177Lu]Lu-NeoB in Patients with Advanced Solid Tumors Overexpressing Gastrin-Releasing Peptide Receptor: Preliminary Safety and Dosimetry Results. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Mittra ES – PersonEntity: Name: NameFull: Solnes LB – PersonEntity: Name: NameFull: van der Veldt AAM – PersonEntity: Name: NameFull: Wong J – PersonEntity: Name: NameFull: Aloj L – PersonEntity: Name: NameFull: Heinrich MC – PersonEntity: Name: NameFull: Chen CT – PersonEntity: Name: NameFull: Rowe SP – PersonEntity: Name: NameFull: Brabander T – PersonEntity: Name: NameFull: Pacey S – PersonEntity: Name: NameFull: Aimone P – PersonEntity: Name: NameFull: Pathak D – PersonEntity: Name: NameFull: Blumenstein L – PersonEntity: Name: NameFull: Liu Y – PersonEntity: Name: NameFull: Iagaru A IsPartOfRelationships: – BibEntity: Dates: – D: 02 M: 02 Text: 2026 Feb 02 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1535-5667 Numbering: – Type: volume Value: 67 – Type: issue Value: 2 Titles: – TitleFull: Journal of nuclear medicine : official publication, Society of Nuclear Medicine Type: main |
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