Mitochondria-targeted gene delivery using fluorinated lipid nanoparticles to alleviate Leber's hereditary optic neuropathy.
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| Title: | Mitochondria-targeted gene delivery using fluorinated lipid nanoparticles to alleviate Leber's hereditary optic neuropathy. |
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| Authors: | Wang Y; State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, Nanjing, China., Zhao M; State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, Nanjing, China., Xie HX; State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, Nanjing, China., Yu HY; State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, Nanjing, China., Yang JS; State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, Nanjing, China., Qie LX; State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, Nanjing, China., Liu NH; State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, Nanjing, China., Chen JQ; State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, Nanjing, China., Yi ZJ; State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, Nanjing, China., Zhou TJ; State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, Nanjing, China., Xing L; State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, Nanjing, China., Cheng XW; Jilin Provincial Key Laboratory of Stress and Cardiovascular Disease, Department of Cardiology and Hypertension, Yanbian University Hospital, Yanji, China., Jiang HL; State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, Nanjing, China. jianghulin3@163.com.; Jilin Provincial Key Laboratory of Stress and Cardiovascular Disease, Department of Cardiology and Hypertension, Yanbian University Hospital, Yanji, China. jianghulin3@163.com.; Joint International Research Laboratory of Target Discovery and New Drug Innovation, MOE, China Pharmaceutical University, Nanjing, China. jianghulin3@163.com.; Department of Precision Medicine, School of Medicine, Sungkyunkwan University, Suwon, Korea. jianghulin3@163.com. |
| Source: | Nature communications [Nat Commun] 2025 Dec 04; Vol. 16 (1), pp. 10891. Date of Electronic Publication: 2025 Dec 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-65874-x |
