View in EDS HTML Full Text PDF Full Text

Neutrophil dysregulation differentiates pediatric septic shock biomarker-based mortality-risk strata: insights from weighted gene co-expression network and transcriptomic analyses.

Saved in:
Bibliographic Details
Title: Neutrophil dysregulation differentiates pediatric septic shock biomarker-based mortality-risk strata: insights from weighted gene co-expression network and transcriptomic analyses.
Authors: Dunwoodie L; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Huang M; Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, United States., Moore AR; Stanford Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, United States.; Center for Biomedical Informatics Research, Department of Medicine, Stanford University School of Medicine, CA, United States., Stanski NL; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States., Standage SW; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States., Kaplan JM; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States., Zingarelli B; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States., Harmon K; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States., Fitzgerald JC; Children's Hospital of Philadelphia, Philadelphia, PA, United States., Weiss SL; Nemours Children's Hospital, Wilmington, DE, United States., Bigham MT; Akron Children's Hospital, Akron, OH, United States., Schwarz AJ; Children's Hospital of Orange County, Orange, CA, United States., Lutfi R; Riley Hospital for Children, Indianapolis, IN, United States., Thomas NJ; Penn State Hershey Children's Hospital, PA, United States., Haileselassie B; Lucile Packard Children's Hospital Stanford, Palo Alto, CA, United States., Jain PN; Heart Center, Children's Health, Division of Cardiology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, United States., Sweeney TE; Inflammatix, Sunnyvale, CA, United States., Kamaleswaran R; Department of Surgery, Duke University School of Medicine, Durham, NC, United States., Atreya MR; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States., Lautz AJ; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.
Source: Frontiers in immunology [Front Immunol] 2025 Nov 19; Vol. 16, pp. 1663704. Date of Electronic Publication: 2025 Nov 19 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41346599
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Neutrophil dysregulation differentiates pediatric septic shock biomarker-based mortality-risk strata: insights from weighted gene co-expression network and transcriptomic analyses.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Dunwoodie+L%22">Dunwoodie L</searchLink>; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.<br /><searchLink fieldCode="AU" term="%22Huang+M%22">Huang M</searchLink>; Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, United States.<br /><searchLink fieldCode="AU" term="%22Moore+AR%22">Moore AR</searchLink>; Stanford Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, United States.; Center for Biomedical Informatics Research, Department of Medicine, Stanford University School of Medicine, CA, United States.<br /><searchLink fieldCode="AU" term="%22Stanski+NL%22">Stanski NL</searchLink>; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.<br /><searchLink fieldCode="AU" term="%22Standage+SW%22">Standage SW</searchLink>; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.<br /><searchLink fieldCode="AU" term="%22Kaplan+JM%22">Kaplan JM</searchLink>; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.<br /><searchLink fieldCode="AU" term="%22Zingarelli+B%22">Zingarelli B</searchLink>; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.<br /><searchLink fieldCode="AU" term="%22Harmon+K%22">Harmon K</searchLink>; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.<br /><searchLink fieldCode="AU" term="%22Fitzgerald+JC%22">Fitzgerald JC</searchLink>; Children's Hospital of Philadelphia, Philadelphia, PA, United States.<br /><searchLink fieldCode="AU" term="%22Weiss+SL%22">Weiss SL</searchLink>; Nemours Children's Hospital, Wilmington, DE, United States.<br /><searchLink fieldCode="AU" term="%22Bigham+MT%22">Bigham MT</searchLink>; Akron Children's Hospital, Akron, OH, United States.<br /><searchLink fieldCode="AU" term="%22Schwarz+AJ%22">Schwarz AJ</searchLink>; Children's Hospital of Orange County, Orange, CA, United States.<br /><searchLink fieldCode="AU" term="%22Lutfi+R%22">Lutfi R</searchLink>; Riley Hospital for Children, Indianapolis, IN, United States.<br /><searchLink fieldCode="AU" term="%22Thomas+NJ%22">Thomas NJ</searchLink>; Penn State Hershey Children's Hospital, PA, United States.<br /><searchLink fieldCode="AU" term="%22Haileselassie+B%22">Haileselassie B</searchLink>; Lucile Packard Children's Hospital Stanford, Palo Alto, CA, United States.<br /><searchLink fieldCode="AU" term="%22Jain+PN%22">Jain PN</searchLink>; Heart Center, Children's Health, Division of Cardiology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, United States.<br /><searchLink fieldCode="AU" term="%22Sweeney+TE%22">Sweeney TE</searchLink>; Inflammatix, Sunnyvale, CA, United States.<br /><searchLink fieldCode="AU" term="%22Kamaleswaran+R%22">Kamaleswaran R</searchLink>; Department of Surgery, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Atreya+MR%22">Atreya MR</searchLink>; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.<br /><searchLink fieldCode="AU" term="%22Lautz+AJ%22">Lautz AJ</searchLink>; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2025 Nov 19; Vol. 16, pp. 1663704. <i>Date of Electronic Publication: </i>2025 Nov 19 (<i>Print Publication: </i>2025).
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41346599
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.3389/fimmu.2025.1663704
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 1663704
    Titles:
      – TitleFull: Neutrophil dysregulation differentiates pediatric septic shock biomarker-based mortality-risk strata: insights from weighted gene co-expression network and transcriptomic analyses.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Dunwoodie L
      – PersonEntity:
          Name:
            NameFull: Huang M
      – PersonEntity:
          Name:
            NameFull: Moore AR
      – PersonEntity:
          Name:
            NameFull: Stanski NL
      – PersonEntity:
          Name:
            NameFull: Standage SW
      – PersonEntity:
          Name:
            NameFull: Kaplan JM
      – PersonEntity:
          Name:
            NameFull: Zingarelli B
      – PersonEntity:
          Name:
            NameFull: Harmon K
      – PersonEntity:
          Name:
            NameFull: Fitzgerald JC
      – PersonEntity:
          Name:
            NameFull: Weiss SL
      – PersonEntity:
          Name:
            NameFull: Bigham MT
      – PersonEntity:
          Name:
            NameFull: Schwarz AJ
      – PersonEntity:
          Name:
            NameFull: Lutfi R
      – PersonEntity:
          Name:
            NameFull: Thomas NJ
      – PersonEntity:
          Name:
            NameFull: Haileselassie B
      – PersonEntity:
          Name:
            NameFull: Jain PN
      – PersonEntity:
          Name:
            NameFull: Sweeney TE
      – PersonEntity:
          Name:
            NameFull: Kamaleswaran R
      – PersonEntity:
          Name:
            NameFull: Atreya MR
      – PersonEntity:
          Name:
            NameFull: Lautz AJ
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 19
              M: 11
              Text: 2025 Nov 19
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1664-3224
          Numbering:
            – Type: volume
              Value: 16
          Titles:
            – TitleFull: Frontiers in immunology
              Type: main
ResultId 1