Interkingdom sensing of fungal tyrosol promotes bacterial antifungal T6SS activity in the murine gut.

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Title: Interkingdom sensing of fungal tyrosol promotes bacterial antifungal T6SS activity in the murine gut.
Authors: Zhu L; State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, P. R. China., Zuo Y; State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, P. R. China.; College of Plant Protection, Northwest A&F University, Yangling, Shaanxi, P. R. China., Cui R; State Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing, P. R. China.; School of Life Sciences, University of Chinese Academy of Sciences, Beijing, P. R. China., Fu P; State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, P. R. China., Liu Y; State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, P. R. China., Wang Z; State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, P. R. China., He X; State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, P. R. China., Yu D; State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, P. R. China., Wei Z; State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, P. R. China., Li S; State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, P. R. China., Wang Y; College of Plant Protection, Northwest A&F University, Yangling, Shaanxi, P. R. China., Li C; State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, P. R. China., Wang Y; State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, P. R. China., Li DF; State Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing, P. R. China. lidefeng@im.ac.cn.; School of Life Sciences, University of Chinese Academy of Sciences, Beijing, P. R. China. lidefeng@im.ac.cn., Liu SJ; State Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing, P. R. China. liusj@sdu.edu.cn.; School of Life Sciences, University of Chinese Academy of Sciences, Beijing, P. R. China. liusj@sdu.edu.cn.; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, P. R. China. liusj@sdu.edu.cn., Shen X; State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, P. R. China. xihuishen@nwsuaf.edu.cn.
Source: Nature microbiology [Nat Microbiol] 2026 Jan; Vol. 11 (1), pp. 240-255. Date of Electronic Publication: 2025 Dec 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101674869 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2058-5276 (Electronic) Linking ISSN: 20585276 NLM ISO Abbreviation: Nat Microbiol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2058-5276
DOI:10.1038/s41564-025-02208-z