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Endothelial cell-targeting aptamer-empowered exosomes accelerate wound healing by promoting specialized angiogenesis in type 1 diabetic mice.

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Title: Endothelial cell-targeting aptamer-empowered exosomes accelerate wound healing by promoting specialized angiogenesis in type 1 diabetic mice.
Authors: Zhao N; Xi'an Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Medical Research, Northwestern Polytechnical University, Xi'an, China., Guo ZZ; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Bai SF; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi'an, China., Gao YF; Xi'an Institute of Tissue Engineering and Regenerative Medicine, Xi'an, China., Lei J; Department of Obstetrics and Gynecology, Affiliated Guangren Hospital, School of Medicine, Xi'an No. 4 Hospital, Xi'an Jiaotong University, Xi'an, China., Li P; Xi'an Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Medical Research, Northwestern Polytechnical University, Xi'an, China., Yu M; Xi'an Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Medical Research, Northwestern Polytechnical University, Xi'an, China., Chen J; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi'an, China.; Department of Oral Implantology, School of Stomatology, The Fourth Military Medical University, Xi'an, China., Xu HK; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi'an, China., Bao LH; Xi'an Institute of Tissue Engineering and Regenerative Medicine, Xi'an, China., Ni H; Xi'an Institute of Tissue Engineering and Regenerative Medicine, Xi'an, China., Jin YH; Department of Obstetrics and Gynecology, Xijing Hospital, The Fourth Military Medical University, Xi'an, China., Qiu XY; Department of Preventive Dentistry, School of Stomatology, The Fourth Military Medical University, Xi'an, China., Shuai Y; Department of Stomatology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.; Department of Stomatology, General Hospital of Eastern Theater Command, PLA, Nanjing, China., Wang QN; Xi'an Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Medical Research, Northwestern Polytechnical University, Xi'an, China., Sui BD; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi'an, China. bingdong@fmmu.edu.cn., Hu CH; Xi'an Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Medical Research, Northwestern Polytechnical University, Xi'an, China. chenghu@nwpu.edu.cn., Zheng CX; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi'an, China. chenxizheng@fmmu.edu.cn.
Source: Stem cell research & therapy [Stem Cell Res Ther] 2025 Dec 07; Vol. 17 (1), pp. 23. Date of Electronic Publication: 2025 Dec 07.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Endothelial cell-targeting aptamer-empowered exosomes accelerate wound healing by promoting specialized angiogenesis in type 1 diabetic mice.
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  Data: <searchLink fieldCode="AU" term="%22Zhao+N%22">Zhao N</searchLink>; Xi'an Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Medical Research, Northwestern Polytechnical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Guo+ZZ%22">Guo ZZ</searchLink>; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Bai+SF%22">Bai SF</searchLink>; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Gao+YF%22">Gao YF</searchLink>; Xi'an Institute of Tissue Engineering and Regenerative Medicine, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Lei+J%22">Lei J</searchLink>; Department of Obstetrics and Gynecology, Affiliated Guangren Hospital, School of Medicine, Xi'an No. 4 Hospital, Xi'an Jiaotong University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Li+P%22">Li P</searchLink>; Xi'an Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Medical Research, Northwestern Polytechnical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Yu+M%22">Yu M</searchLink>; Xi'an Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Medical Research, Northwestern Polytechnical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi'an, China.; Department of Oral Implantology, School of Stomatology, The Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Xu+HK%22">Xu HK</searchLink>; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Bao+LH%22">Bao LH</searchLink>; Xi'an Institute of Tissue Engineering and Regenerative Medicine, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Ni+H%22">Ni H</searchLink>; Xi'an Institute of Tissue Engineering and Regenerative Medicine, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Jin+YH%22">Jin YH</searchLink>; Department of Obstetrics and Gynecology, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Qiu+XY%22">Qiu XY</searchLink>; Department of Preventive Dentistry, School of Stomatology, The Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Shuai+Y%22">Shuai Y</searchLink>; Department of Stomatology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.; Department of Stomatology, General Hospital of Eastern Theater Command, PLA, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Wang+QN%22">Wang QN</searchLink>; Xi'an Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Medical Research, Northwestern Polytechnical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Sui+BD%22">Sui BD</searchLink>; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi'an, China. bingdong@fmmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Hu+CH%22">Hu CH</searchLink>; Xi'an Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Medical Research, Northwestern Polytechnical University, Xi'an, China. chenghu@nwpu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zheng+CX%22">Zheng CX</searchLink>; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi'an, China. chenxizheng@fmmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101527581%22">Stem cell research & therapy</searchLink> [Stem Cell Res Ther] 2025 Dec 07; Vol. 17 (1), pp. 23. <i>Date of Electronic Publication: </i>2025 Dec 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101527581 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-6512 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217576512%22">17576512 </searchLink><i>NLM ISO Abbreviation: </i>Stem Cell Res Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s13287-025-04846-w
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              Text: 2025 Dec 07
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