IER3 drives the transition from sepsis-associated AKI to CKD by suppressing the mitochondrial translocation of PRDX5.
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| Title: | IER3 drives the transition from sepsis-associated AKI to CKD by suppressing the mitochondrial translocation of PRDX5. |
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| Authors: | Dou Q; Department of Nephrology, Daping Hospital, Chongqing Key Laboratory of Precision Diagnosis and Treatment for Kidney Diseases, Army Medical University, Chongqing, 400042, China.; Department of Nephrology, Metabolism and Immunology Laboratory for Urological Diseases ，The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China., Tong H; Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China., Chen J; Department of Nephrology, Daping Hospital, Chongqing Key Laboratory of Precision Diagnosis and Treatment for Kidney Diseases, Army Medical University, Chongqing, 400042, China., Yi X; Department of Nephrology, Daping Hospital, Chongqing Key Laboratory of Precision Diagnosis and Treatment for Kidney Diseases, Army Medical University, Chongqing, 400042, China., Bai L; Department of Nephrology, Daping Hospital, Chongqing Key Laboratory of Precision Diagnosis and Treatment for Kidney Diseases, Army Medical University, Chongqing, 400042, China., He J; Department of Nephrology, Daping Hospital, Chongqing Key Laboratory of Precision Diagnosis and Treatment for Kidney Diseases, Army Medical University, Chongqing, 400042, China., Chen K; Department of Nephrology, Daping Hospital, Chongqing Key Laboratory of Precision Diagnosis and Treatment for Kidney Diseases, Army Medical University, Chongqing, 400042, China. chenkh@tmmu.edu.cn.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, 400042, China. chenkh@tmmu.edu.cn. |
| Source: | Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2025 Dec 08; Vol. 82 (1), pp. 439. Date of Electronic Publication: 2025 Dec 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1420-9071 |
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| DOI: | 10.1007/s00018-025-05963-8 |
