Functional genomics for improving adoptive T-cell transfer therapies.

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Title: Functional genomics for improving adoptive T-cell transfer therapies.
Authors: Skeate JG; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.; Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA., Lee CJ; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA.; Department of Genetics, Cell Biology and Development, University of Minnesota, Twin Cities, Minneapolis, Minnesota, USA., Stewart C; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.; T Cell Engineering Laboratory Program, Mayo Clinic, Rochester, Minnesota, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, Minnesota, USA., Fischbach MJ; Department of Computer Science and Engineering, University of Minnesota, Minneapolis, Minnesota, USA.; Graduate Program in Bioinformatics and Computational Biology (BICB), University of Minnesota, Minneapolis, Minnesota, USA.; Department of Immunology, Mayo Clinic, Rochester, Minnesota, USA., Kar B; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.; Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA., Tsai AK; Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA.; Department of Medicine, Division of Hematology, Oncology, and Transplantation, University of Minnesota, Minneapolis, Minnesota, USA.; Center for Immunology, University of Minnesota, Minneapolis, Minnesota, USA., Kenderian SS; T Cell Engineering Laboratory Program, Mayo Clinic, Rochester, Minnesota, USA.; Department of Immunology, Mayo Clinic, Rochester, Minnesota, USA.; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.; Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, Minnesota, USA.; Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, USA., Stromnes IM; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA.; Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA.; Department of Medicine, Division of Hematology, Oncology, and Transplantation, University of Minnesota, Minneapolis, Minnesota, USA., Largaespada DA; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.; Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA.; Department of Genetics, Cell Biology and Development, University of Minnesota, Twin Cities, Minneapolis, Minnesota, USA., Moriarity BS; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.; Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA., Rogers LM; Department of Immunology, Mayo Clinic, Rochester, Minnesota, USA Rogers.Laura@mayo.edu.; Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, Minnesota, USA.
Source: Journal for immunotherapy of cancer [J Immunother Cancer] 2025 Dec 09; Vol. 13 (12). Date of Electronic Publication: 2025 Dec 09.
Publication Type: Journal Article; Review
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2051-1426
DOI:10.1136/jitc-2025-013286