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Mapping the genetic landscape across 14 psychiatric disorders.

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Title: Mapping the genetic landscape across 14 psychiatric disorders.
Authors: Grotzinger AD; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA. andrew.grotzinger@colorado.edu.; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA. andrew.grotzinger@colorado.edu., Werme J; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Peyrot WJ; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Department of Psychiatry, Amsterdam UMC, Amsterdam, The Netherlands., Frei O; Center for Bioinformatics, Department of Informatics, University of Oslo, Oslo, Norway.; NORMENT Centre, Institute of Clinical Medicine, University of Oslo and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., de Leeuw C; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Bicks LK; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Guo Q; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.; Discovery Biomarker, Amgen, Thousand Oaks, CA, USA., Margolis MP; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Coombes BJ; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Batzler A; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Pazdernik V; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Biernacka JM; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.; Department of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, USA., Andreassen OA; NORMENT Centre, Institute of Clinical Medicine, University of Oslo and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; KG Jebsen Centre for Neurodevelopment, University of Oslo, Oslo, Norway., Anttila V; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Børglum AD; Center for Genomics and Personalized Medicine, CGPM, Aarhus, Denmark.; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; The Lundbeck Foundation Initiative for Integrative Psychiatric Research-iPSYCH, Aarhus, Denmark., Breen G; Social Genetic and Developmental Psychiatry Centre, King's College London, London, UK., Cai N; Computational Health Centre, Helmholtz Munich, Neuherberg, Germany.; Department of Biosystems Science and Engineering, ETH Zurich, Zurich, Switzerland.; Department of Medicine, Technical University of Munich, Munich, Germany.; Helmholtz Pioneer Campus, Helmholtz Munich, Neuherberg, Germany., Demontis D; Center for Genomics and Personalized Medicine, CGPM, Aarhus, Denmark.; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; The Lundbeck Foundation Initiative for Integrative Psychiatric Research-iPSYCH, Aarhus, Denmark.; The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Edenberg HJ; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA., Faraone SV; Department of Neuroscience and Physiology, Norton College of Medicine, SUNY Upstate Medical University, Syracuse, NY, USA.; Department of Psychiatry, Norton College of Medicine, SUNY Upstate Medical Universitiy, Syracuse, NY, USA., Franke B; Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands., Gandal MJ; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Lifespan Brain Institute at Penn Med and the Children's Hospital of Philadelphia, Philadelphia, PA, USA., Gelernter J; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; VA Connecticut Healthcare Center, West Haven, CT, USA., Hatoum AS; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA., Hettema JM; Department of Psychiatry and Behavioral Sciences, Texas A&M University, College Station, TX, USA., Johnson EC; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA., Jonas KG; Department of Psychiatry & Behavioral Health, Stony Brook University, New York, NY, USA., Knowles JA; Department of Genetics, Rutgers University, Piscataway, NJ, USA.; Human Genetics Institute of New Jersey (HGINJ), Rutgers University, Piscataway, NJ, USA., Koenen KC; Broad Institute of MIT and Harvard, Boston, MA, USA.; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA.; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA., Maihofer AX; Center of Excellence for Stress and Mental Health, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA.; Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Research Service, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA., Mallard TT; Center for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Mattheisen M; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, Stockholm, Sweden.; Department of Community Health and Epidemiology and Faculty of Computer Science, Dalhousie University, Halifax, Nova Scotia, Canada.; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany., Mitchell KS; Department of Psychiatry, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; National Center for PTSD at VA Boston Healthcare System, Boston, MA, USA., Neale BM; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Nievergelt CM; Center of Excellence for Stress and Mental Health, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA.; Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Research Service, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA., Nurnberger JI; Department of Medical and Molecular Genetics, Department of Psychiatry, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., O'Connell KS; NORMENT Centre, Institute of Clinical Medicine, University of Oslo and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Peterson RE; Department of Psychiatry and Behavioral Sciences, Institute for Genomics in Health, SUNY Downstate Health Sciences University, New York, NY, USA., Robinson EB; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Genomic Medicine and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA., Sanchez-Roige SS; Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Department of Medicine, Division of Genetic Medicine, Vanderbilt University, Nashville, TN, USA.; Institute for Genomic Medicine, University of California San Diego, San Diego, CA, USA., Santangelo SL; Center for Clinical and Translational Science, Maine Health Institute for Research, Portland, ME, USA.; Department of Psychiatry, Tufts University School of Medicine, Boston, MA, USA., Scharf JM; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA., Stefansson H; Amgen-deCODE Genetics, Reykjavik, Iceland., Stefansson K; Amgen-deCODE Genetics, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavík, Iceland., Stein MB; Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA.; VA San Diego Healthcare System, San Diego, CA, USA., Strom NI; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, Stockholm, Sweden.; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany.; Department of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany., Thornton LM; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Tucker-Drob EM; Center on Aging and Population Sciences, University of Texas at Austin, Austin, TX, USA.; Department of Psychology, University of Texas at Austin, Austin, TX, USA.; Population Research Center, University of Texas at Austin, Austin, TX, USA., Verhulst B; Department of Psychiatry and Behavioral Sciences, Texas A&M University, College Station, TX, USA., Waldman ID; Department of Psychology, Emory University, Atlanta, GA, USA., Walters GB; Amgen-deCODE Genetics, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavík, Iceland., Wray NR; Department of Psychiatry, University of Oxford, Oxford, UK.; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Yu D; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA., Lee PH; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Kendler KS; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.; Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA., Smoller JW; Broad Institute of MIT and Harvard, Boston, MA, USA. jsmoller@mgb.org.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA. jsmoller@mgb.org.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. jsmoller@mgb.org.
Corporate Authors: Anxiety Disorders Working Group of the Psychiatric Genomics Consortium, Attention-Deficit/Hyperactivity Disorder (ADHD) Working Group of the Psychiatric Genomics Consortium, Autism Spectrum Disorders Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Nicotine Dependence GenOmics (iNDiGO) Consortium, Obsessive-Compulsive Disorder and Tourette Syndrome Working Group of the Psychiatric Genomics Consortium, Post-Traumatic Stress Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Substance Use Disorders Working Group of the Psychiatric Genomics Consortium
Source: Nature [Nature] 2026 Jan; Vol. 649 (8096), pp. 406-415. Date of Electronic Publication: 2025 Dec 10.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mapping the genetic landscape across 14 psychiatric disorders.
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  Data: <searchLink fieldCode="AU" term="%22Grotzinger+AD%22">Grotzinger AD</searchLink>; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA. andrew.grotzinger@colorado.edu.; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA. andrew.grotzinger@colorado.edu.<br /><searchLink fieldCode="AU" term="%22Werme+J%22">Werme J</searchLink>; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Peyrot+WJ%22">Peyrot WJ</searchLink>; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Department of Psychiatry, Amsterdam UMC, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Frei+O%22">Frei O</searchLink>; Center for Bioinformatics, Department of Informatics, University of Oslo, Oslo, Norway.; NORMENT Centre, Institute of Clinical Medicine, University of Oslo and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22de+Leeuw+C%22">de Leeuw C</searchLink>; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bicks+LK%22">Bicks LK</searchLink>; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Guo+Q%22">Guo Q</searchLink>; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.; Discovery Biomarker, Amgen, Thousand Oaks, CA, USA.<br /><searchLink fieldCode="AU" term="%22Margolis+MP%22">Margolis MP</searchLink>; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Coombes+BJ%22">Coombes BJ</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Batzler+A%22">Batzler A</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Pazdernik+V%22">Pazdernik V</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Biernacka+JM%22">Biernacka JM</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.; Department of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Andreassen+OA%22">Andreassen OA</searchLink>; NORMENT Centre, Institute of Clinical Medicine, University of Oslo and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; KG Jebsen Centre for Neurodevelopment, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Anttila+V%22">Anttila V</searchLink>; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Børglum+AD%22">Børglum AD</searchLink>; Center for Genomics and Personalized Medicine, CGPM, Aarhus, Denmark.; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; The Lundbeck Foundation Initiative for Integrative Psychiatric Research-iPSYCH, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Breen+G%22">Breen G</searchLink>; Social Genetic and Developmental Psychiatry Centre, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Cai+N%22">Cai N</searchLink>; Computational Health Centre, Helmholtz Munich, Neuherberg, Germany.; Department of Biosystems Science and Engineering, ETH Zurich, Zurich, Switzerland.; Department of Medicine, Technical University of Munich, Munich, Germany.; Helmholtz Pioneer Campus, Helmholtz Munich, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Demontis+D%22">Demontis D</searchLink>; Center for Genomics and Personalized Medicine, CGPM, Aarhus, Denmark.; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; The Lundbeck Foundation Initiative for Integrative Psychiatric Research-iPSYCH, Aarhus, Denmark.; The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Edenberg+HJ%22">Edenberg HJ</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Faraone+SV%22">Faraone SV</searchLink>; Department of Neuroscience and Physiology, Norton College of Medicine, SUNY Upstate Medical University, Syracuse, NY, USA.; Department of Psychiatry, Norton College of Medicine, SUNY Upstate Medical Universitiy, Syracuse, NY, USA.<br /><searchLink fieldCode="AU" term="%22Franke+B%22">Franke B</searchLink>; Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Gandal+MJ%22">Gandal MJ</searchLink>; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Lifespan Brain Institute at Penn Med and the Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Gelernter+J%22">Gelernter J</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; VA Connecticut Healthcare Center, West Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Hatoum+AS%22">Hatoum AS</searchLink>; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Hettema+JM%22">Hettema JM</searchLink>; Department of Psychiatry and Behavioral Sciences, Texas A&M University, College Station, TX, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+EC%22">Johnson EC</searchLink>; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Jonas+KG%22">Jonas KG</searchLink>; Department of Psychiatry & Behavioral Health, Stony Brook University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Knowles+JA%22">Knowles JA</searchLink>; Department of Genetics, Rutgers University, Piscataway, NJ, USA.; Human Genetics Institute of New Jersey (HGINJ), Rutgers University, Piscataway, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Koenen+KC%22">Koenen KC</searchLink>; Broad Institute of MIT and Harvard, Boston, MA, USA.; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA.; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Maihofer+AX%22">Maihofer AX</searchLink>; Center of Excellence for Stress and Mental Health, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA.; Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Research Service, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Mallard+TT%22">Mallard TT</searchLink>; Center for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Mattheisen+M%22">Mattheisen M</searchLink>; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, Stockholm, Sweden.; Department of Community Health and Epidemiology and Faculty of Computer Science, Dalhousie University, Halifax, Nova Scotia, Canada.; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Mitchell+KS%22">Mitchell KS</searchLink>; Department of Psychiatry, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; National Center for PTSD at VA Boston Healthcare System, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Neale+BM%22">Neale BM</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Nievergelt+CM%22">Nievergelt CM</searchLink>; Center of Excellence for Stress and Mental Health, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA.; Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Research Service, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Nurnberger+JI%22">Nurnberger JI</searchLink>; Department of Medical and Molecular Genetics, Department of Psychiatry, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22O'Connell+KS%22">O'Connell KS</searchLink>; NORMENT Centre, Institute of Clinical Medicine, University of Oslo and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Peterson+RE%22">Peterson RE</searchLink>; Department of Psychiatry and Behavioral Sciences, Institute for Genomics in Health, SUNY Downstate Health Sciences University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Robinson+EB%22">Robinson EB</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Genomic Medicine and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sanchez-Roige+SS%22">Sanchez-Roige SS</searchLink>; Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Department of Medicine, Division of Genetic Medicine, Vanderbilt University, Nashville, TN, USA.; Institute for Genomic Medicine, University of California San Diego, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Santangelo+SL%22">Santangelo SL</searchLink>; Center for Clinical and Translational Science, Maine Health Institute for Research, Portland, ME, USA.; Department of Psychiatry, Tufts University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Scharf+JM%22">Scharf JM</searchLink>; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Stefansson+H%22">Stefansson H</searchLink>; Amgen-deCODE Genetics, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Stefansson+K%22">Stefansson K</searchLink>; Amgen-deCODE Genetics, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavík, Iceland.<br /><searchLink fieldCode="AU" term="%22Stein+MB%22">Stein MB</searchLink>; Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA.; VA San Diego Healthcare System, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Strom+NI%22">Strom NI</searchLink>; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, Stockholm, Sweden.; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany.; Department of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Thornton+LM%22">Thornton LM</searchLink>; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Tucker-Drob+EM%22">Tucker-Drob EM</searchLink>; Center on Aging and Population Sciences, University of Texas at Austin, Austin, TX, USA.; Department of Psychology, University of Texas at Austin, Austin, TX, USA.; Population Research Center, University of Texas at Austin, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Verhulst+B%22">Verhulst B</searchLink>; Department of Psychiatry and Behavioral Sciences, Texas A&M University, College Station, TX, USA.<br /><searchLink fieldCode="AU" term="%22Waldman+ID%22">Waldman ID</searchLink>; Department of Psychology, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Walters+GB%22">Walters GB</searchLink>; Amgen-deCODE Genetics, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavík, Iceland.<br /><searchLink fieldCode="AU" term="%22Wray+NR%22">Wray NR</searchLink>; Department of Psychiatry, University of Oxford, Oxford, UK.; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Yu+D%22">Yu D</searchLink>; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lee+PH%22">Lee PH</searchLink>; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kendler+KS%22">Kendler KS</searchLink>; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.; Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Smoller+JW%22">Smoller JW</searchLink>; Broad Institute of MIT and Harvard, Boston, MA, USA. jsmoller@mgb.org.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA. jsmoller@mgb.org.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. jsmoller@mgb.org.
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  Data: <searchLink fieldCode="CA" term="%22Anxiety+Disorders+Working+Group+of+the+Psychiatric+Genomics+Consortium%22">Anxiety Disorders Working Group of the Psychiatric Genomics Consortium</searchLink><br /><searchLink fieldCode="CA" term="%22Attention-Deficit%2FHyperactivity+Disorder+%28ADHD%29+Working+Group+of+the+Psychiatric+Genomics+Consortium%22">Attention-Deficit/Hyperactivity Disorder (ADHD) Working Group of the Psychiatric Genomics Consortium</searchLink><br /><searchLink fieldCode="CA" term="%22Autism+Spectrum+Disorders+Working+Group+of+the+Psychiatric+Genomics+Consortium%22">Autism Spectrum Disorders Working Group of the Psychiatric Genomics Consortium</searchLink><br /><searchLink fieldCode="CA" term="%22Bipolar+Disorder+Working+Group+of+the+Psychiatric+Genomics+Consortium%22">Bipolar Disorder Working Group of the Psychiatric Genomics Consortium</searchLink><br /><searchLink fieldCode="CA" term="%22Eating+Disorders+Working+Group+of+the+Psychiatric+Genomics+Consortium%22">Eating Disorders Working Group of the Psychiatric Genomics Consortium</searchLink><br /><searchLink fieldCode="CA" term="%22Major+Depressive+Disorder+Working+Group+of+the+Psychiatric+Genomics+Consortium%22">Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium</searchLink><br /><searchLink fieldCode="CA" term="%22Nicotine+Dependence+GenOmics+%28iNDiGO%29+Consortium%22">Nicotine Dependence GenOmics (iNDiGO) Consortium</searchLink><br /><searchLink fieldCode="CA" term="%22Obsessive-Compulsive+Disorder+and+Tourette+Syndrome+Working+Group+of+the+Psychiatric+Genomics+Consortium%22">Obsessive-Compulsive Disorder and Tourette Syndrome Working Group of the Psychiatric Genomics Consortium</searchLink><br /><searchLink fieldCode="CA" term="%22Post-Traumatic+Stress+Disorder+Working+Group+of+the+Psychiatric+Genomics+Consortium%22">Post-Traumatic Stress Disorder Working Group of the Psychiatric Genomics Consortium</searchLink><br /><searchLink fieldCode="CA" term="%22Schizophrenia+Working+Group+of+the+Psychiatric+Genomics+Consortium%22">Schizophrenia Working Group of the Psychiatric Genomics Consortium</searchLink><br /><searchLink fieldCode="CA" term="%22Substance+Use+Disorders+Working+Group+of+the+Psychiatric+Genomics+Consortium%22">Substance Use Disorders Working Group of the Psychiatric Genomics Consortium</searchLink>
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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2026 Jan; Vol. 649 (8096), pp. 406-415. <i>Date of Electronic Publication: </i>2025 Dec 10.
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  Data: Journal Article; Research Support, N.I.H., Extramural
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  Label: Journal Info
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0410462 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-4687 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200280836%22">00280836 </searchLink><i>NLM ISO Abbreviation: </i>Nature <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41372416
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        Value: 10.1038/s41586-025-09820-3
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        Text: English
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      – TitleFull: Mapping the genetic landscape across 14 psychiatric disorders.
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              Text: 2026 Jan
              Type: published
              Y: 2026
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