Concurrent detection of cognitive impairment and amyloid positivity with a multimodal machine learning-enabled digital cognitive assessment.

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Title: Concurrent detection of cognitive impairment and amyloid positivity with a multimodal machine learning-enabled digital cognitive assessment.
Authors: Jannati A; Department of Neurology, Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA. ajannati@linus.health.; Linus Health, Inc, 280 Summer Street, 10th Floor, Boston, MA, 02210, USA. ajannati@linus.health., Thompson K; Linus Health, Inc, 280 Summer Street, 10th Floor, Boston, MA, 02210, USA., Toro-Serey C; Linus Health, Inc, 280 Summer Street, 10th Floor, Boston, MA, 02210, USA., Gomes-Osman J; Department of Neurology, University of Miami Miller School of Medicine, 1600 NW 10th Avenue, Miami, FL, 33136, USA., Banks RE; Department of Communicative Sciences & Disorders, Michigan State University, 404 Wilson Rd, East Lansing, MI, 48824, USA., Higgins C; Linus Health, Inc, 280 Summer Street, 10th Floor, Boston, MA, 02210, USA., Showalter J; Linus Health, Inc, 280 Summer Street, 10th Floor, Boston, MA, 02210, USA., Bates D; Linus Health, Inc, 280 Summer Street, 10th Floor, Boston, MA, 02210, USA., Tobyne S; Linus Health, Inc, 280 Summer Street, 10th Floor, Boston, MA, 02210, USA., Pascual-Leone A; Department of Neurology, Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA. apleone@hsl.harvard.edu.; Linus Health, Inc, 280 Summer Street, 10th Floor, Boston, MA, 02210, USA. apleone@hsl.harvard.edu.; Hinda and Arthur Marcus Institute for Aging Research and Deanna and Sidney Wolk Center for Memory Health, Hebrew SeniorLife, 1200 Centre St, Boston, MA, 02131, USA. apleone@hsl.harvard.edu.; Deanna and Sidney Wolk Center for Memory Health Hebrew SeniorLife, Harvard Medical School, 1200 Centre St, Boston, MA, 02131, USA. apleone@hsl.harvard.edu.
Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2025 Dec 11; Vol. 17 (1), pp. 261. Date of Electronic Publication: 2025 Dec 11.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1758-9193
DOI:10.1186/s13195-025-01913-5