Early life stress induces social behavioral deficits and peripheral biomarker alterations in adolescence that perpetuate intergenerationally.

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Title: Early life stress induces social behavioral deficits and peripheral biomarker alterations in adolescence that perpetuate intergenerationally.
Authors: McGowan JC; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Basic Neuroscience Division, Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA, USA., Katzenstein JL; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Basic Neuroscience Division, Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA, USA.; Current address: Putnam Associates, New York, NY, USA., Chace NS; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Basic Neuroscience Division, Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA, USA., Wagner-Sanchez C; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Jordan High School, Fulshear, TX, USA., Okotore T; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Department of Neuroscience, University of Michigan, MI, USA., Ogunfowora T; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Center for Biomedical Engineering, Brown University, Providence, RI, USA., Baram TZ; Department of Pediatrics, University of California, Irvine, CA, USA.; Department of Neurology, University of California, Irvine, CA, USA.; Department of Anatomy & Neurobiology, University of California, Irvine, CA, USA., Folorunso OO; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Basic Neuroscience Division, Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA, USA., Carlezon WA Jr; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Basic Neuroscience Division, Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Dec 01. Date of Electronic Publication: 2025 Dec 01.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2025.11.27.690841