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Early life stress induces social behavioral deficits and peripheral biomarker alterations in adolescence that perpetuate intergenerationally.

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Title: Early life stress induces social behavioral deficits and peripheral biomarker alterations in adolescence that perpetuate intergenerationally.
Authors: McGowan JC; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Basic Neuroscience Division, Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA, USA., Katzenstein JL; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Basic Neuroscience Division, Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA, USA.; Current address: Putnam Associates, New York, NY, USA., Chace NS; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Basic Neuroscience Division, Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA, USA., Wagner-Sanchez C; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Jordan High School, Fulshear, TX, USA., Okotore T; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Department of Neuroscience, University of Michigan, MI, USA., Ogunfowora T; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Center for Biomedical Engineering, Brown University, Providence, RI, USA., Baram TZ; Department of Pediatrics, University of California, Irvine, CA, USA.; Department of Neurology, University of California, Irvine, CA, USA.; Department of Anatomy & Neurobiology, University of California, Irvine, CA, USA., Folorunso OO; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Basic Neuroscience Division, Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA, USA., Carlezon WA Jr; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Basic Neuroscience Division, Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Dec 01. Date of Electronic Publication: 2025 Dec 01.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Early life stress induces social behavioral deficits and peripheral biomarker alterations in adolescence that perpetuate intergenerationally.
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  Data: <searchLink fieldCode="AU" term="%22McGowan+JC%22">McGowan JC</searchLink>; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Basic Neuroscience Division, Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA, USA.<br /><searchLink fieldCode="AU" term="%22Katzenstein+JL%22">Katzenstein JL</searchLink>; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Basic Neuroscience Division, Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA, USA.; Current address: Putnam Associates, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chace+NS%22">Chace NS</searchLink>; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Basic Neuroscience Division, Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wagner-Sanchez+C%22">Wagner-Sanchez C</searchLink>; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Jordan High School, Fulshear, TX, USA.<br /><searchLink fieldCode="AU" term="%22Okotore+T%22">Okotore T</searchLink>; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Department of Neuroscience, University of Michigan, MI, USA.<br /><searchLink fieldCode="AU" term="%22Ogunfowora+T%22">Ogunfowora T</searchLink>; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Center for Biomedical Engineering, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Baram+TZ%22">Baram TZ</searchLink>; Department of Pediatrics, University of California, Irvine, CA, USA.; Department of Neurology, University of California, Irvine, CA, USA.; Department of Anatomy & Neurobiology, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Folorunso+OO%22">Folorunso OO</searchLink>; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Basic Neuroscience Division, Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA, USA.<br /><searchLink fieldCode="AU" term="%22Carlezon+WA+Jr%22">Carlezon WA Jr</searchLink>; Department of Psychiatry, Harvard Medical School, Boston, MA, USA, 02115.; Basic Neuroscience Division, Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Dec 01. <i>Date of Electronic Publication: </i>2025 Dec 01.
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        Value: 10.1101/2025.11.27.690841
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              Text: 2025 Dec 01
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