Cost Effectiveness of Local Anaesthetic Transperineal Versus Transrectal Biopsy: Results from the TRANSLATE Study.

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Title: Cost Effectiveness of Local Anaesthetic Transperineal Versus Transrectal Biopsy: Results from the TRANSLATE Study.
Authors: Little M; Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Wolstenholme J; Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Landeiro F; Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Marian IR; Oxford Clinical Trials Research Unit (OCTRU), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Williams R; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Surgical Intervention Trials Unit (SITU), University of Oxford, Oxford, UK., Francisco Lopez J; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK., Mercader C; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK., Raslan M; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK., Berridge C; Department of Urology, University Hospitals Coventry and Warwickshire NHS Trust, University Hospital, Coventry, UK., Whitburn J; Department of Urology, Buckinghamshire Healthcare NHS Trust, Wycombe Hospital, High Wycombe, UK., Campbell T; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK., Tuck S; Oxfordshire Prostate Cancer Support Group, Oxford, UK., Barber VS; Oxford Clinical Trials Research Unit (OCTRU), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Scaife J; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Surgical Intervention Trials Unit (SITU), University of Oxford, Oxford, UK., Hewitt A; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Surgical Intervention Trials Unit (SITU), University of Oxford, Oxford, UK., Taylor A; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Surgical Intervention Trials Unit (SITU), University of Oxford, Oxford, UK., Ooms A; Oxford Clinical Trials Research Unit (OCTRU), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Ghosh S; Department of Radiology, Maidstone and Tunbridge Wells NHS Trust, Maidstone Hospital, Maidstone, UK., Reynard JM; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK., Hamdy FC; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Surgical Intervention Trials Unit (SITU), University of Oxford, Oxford, UK; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK., Liew MPC; Department of Urology, Wrightington, Wigan and Leigh Teaching Hospitals NHS Foundation Trust, Wigan, UK., Leslie T; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK; Department of Urology, Milton Keynes University Hospital NHS Foundation Trust, Milton Keynes Hospital, Milton Keynes, UK., Catto JWF; Division of Clinical Medicine, University of Sheffield and Department of Urology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Rosario DJ; Division of Clinical Medicine, University of Sheffield and Department of Urology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Omer A; Department of Urology, University Hospitals Coventry and Warwickshire NHS Trust, University Hospital, Coventry, UK., Good DW; Department of Urology, NHS Lothian, Western General Hospital, Edinburgh, UK., Gray R; Department of Urology, Buckinghamshire Healthcare NHS Trust, Wycombe Hospital, High Wycombe, UK., Kommu S; Department of Urology, East Kent Hospitals University NHS Foundation Trust, Kent and Canterbury Hospital, Canterbury, UK., Chung D; Department of Urology, Cardiff and Vale University Health Board, University Hospital of Wales, Cardiff, UK., Wells H; Department of Urology, Cardiff and Vale University Health Board, University Hospital of Wales, Cardiff, UK., Narahari K; Department of Urology, Cardiff and Vale University Health Board, University Hospital of Wales, Cardiff, UK., Macpherson RE; Department of Radiology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK., Verrill C; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Department of Cellular Pathology, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK; Oxford NIHR Biomedical Research Centre, Oxford, UK., Eddy B; Department of Urology, East Kent Hospitals University NHS Foundation Trust, Kent and Canterbury Hospital, Canterbury, UK., Yamamoto H; Department of Urology, Maidstone and Tunbridge Wells NHS Trust, Maidstone Hospital, Maidstone, UK., Bryant RJ; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Surgical Intervention Trials Unit (SITU), University of Oxford, Oxford, UK; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK. Electronic address: richard.bryant@nds.ox.ac.uk., Lamb AD; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK; Barts Cancer Institute, Queen Mary University of London, London, UK.
Corporate Authors: TRANSLATE Trial Study Group
Source: European urology focus [Eur Urol Focus] 2026 Mar; Vol. 12 (2), pp. 227-236. Date of Electronic Publication: 2025 Dec 12.
Publication Type: Journal Article; Randomized Controlled Trial; Comparative Study; Multicenter Study
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101665661 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2405-4569 (Electronic) Linking ISSN: 24054569 NLM ISO Abbreviation: Eur Urol Focus Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cost Effectiveness of Local Anaesthetic Transperineal Versus Transrectal Biopsy: Results from the TRANSLATE Study.
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  Data: <searchLink fieldCode="AU" term="%22Little+M%22">Little M</searchLink>; Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Wolstenholme+J%22">Wolstenholme J</searchLink>; Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Landeiro+F%22">Landeiro F</searchLink>; Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Marian+IR%22">Marian IR</searchLink>; Oxford Clinical Trials Research Unit (OCTRU), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Williams+R%22">Williams R</searchLink>; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Surgical Intervention Trials Unit (SITU), University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Francisco+Lopez+J%22">Francisco Lopez J</searchLink>; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Mercader+C%22">Mercader C</searchLink>; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Raslan+M%22">Raslan M</searchLink>; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Berridge+C%22">Berridge C</searchLink>; Department of Urology, University Hospitals Coventry and Warwickshire NHS Trust, University Hospital, Coventry, UK.<br /><searchLink fieldCode="AU" term="%22Whitburn+J%22">Whitburn J</searchLink>; Department of Urology, Buckinghamshire Healthcare NHS Trust, Wycombe Hospital, High Wycombe, UK.<br /><searchLink fieldCode="AU" term="%22Campbell+T%22">Campbell T</searchLink>; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Tuck+S%22">Tuck S</searchLink>; Oxfordshire Prostate Cancer Support Group, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Barber+VS%22">Barber VS</searchLink>; Oxford Clinical Trials Research Unit (OCTRU), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Scaife+J%22">Scaife J</searchLink>; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Surgical Intervention Trials Unit (SITU), University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Hewitt+A%22">Hewitt A</searchLink>; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Surgical Intervention Trials Unit (SITU), University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Taylor+A%22">Taylor A</searchLink>; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Surgical Intervention Trials Unit (SITU), University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Ooms+A%22">Ooms A</searchLink>; Oxford Clinical Trials Research Unit (OCTRU), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Ghosh+S%22">Ghosh S</searchLink>; Department of Radiology, Maidstone and Tunbridge Wells NHS Trust, Maidstone Hospital, Maidstone, UK.<br /><searchLink fieldCode="AU" term="%22Reynard+JM%22">Reynard JM</searchLink>; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Hamdy+FC%22">Hamdy FC</searchLink>; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Surgical Intervention Trials Unit (SITU), University of Oxford, Oxford, UK; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Liew+MPC%22">Liew MPC</searchLink>; Department of Urology, Wrightington, Wigan and Leigh Teaching Hospitals NHS Foundation Trust, Wigan, UK.<br /><searchLink fieldCode="AU" term="%22Leslie+T%22">Leslie T</searchLink>; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK; Department of Urology, Milton Keynes University Hospital NHS Foundation Trust, Milton Keynes Hospital, Milton Keynes, UK.<br /><searchLink fieldCode="AU" term="%22Catto+JWF%22">Catto JWF</searchLink>; Division of Clinical Medicine, University of Sheffield and Department of Urology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Rosario+DJ%22">Rosario DJ</searchLink>; Division of Clinical Medicine, University of Sheffield and Department of Urology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Omer+A%22">Omer A</searchLink>; Department of Urology, University Hospitals Coventry and Warwickshire NHS Trust, University Hospital, Coventry, UK.<br /><searchLink fieldCode="AU" term="%22Good+DW%22">Good DW</searchLink>; Department of Urology, NHS Lothian, Western General Hospital, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Gray+R%22">Gray R</searchLink>; Department of Urology, Buckinghamshire Healthcare NHS Trust, Wycombe Hospital, High Wycombe, UK.<br /><searchLink fieldCode="AU" term="%22Kommu+S%22">Kommu S</searchLink>; Department of Urology, East Kent Hospitals University NHS Foundation Trust, Kent and Canterbury Hospital, Canterbury, UK.<br /><searchLink fieldCode="AU" term="%22Chung+D%22">Chung D</searchLink>; Department of Urology, Cardiff and Vale University Health Board, University Hospital of Wales, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Wells+H%22">Wells H</searchLink>; Department of Urology, Cardiff and Vale University Health Board, University Hospital of Wales, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Narahari+K%22">Narahari K</searchLink>; Department of Urology, Cardiff and Vale University Health Board, University Hospital of Wales, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Macpherson+RE%22">Macpherson RE</searchLink>; Department of Radiology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Verrill+C%22">Verrill C</searchLink>; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Department of Cellular Pathology, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK; Oxford NIHR Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Eddy+B%22">Eddy B</searchLink>; Department of Urology, East Kent Hospitals University NHS Foundation Trust, Kent and Canterbury Hospital, Canterbury, UK.<br /><searchLink fieldCode="AU" term="%22Yamamoto+H%22">Yamamoto H</searchLink>; Department of Urology, Maidstone and Tunbridge Wells NHS Trust, Maidstone Hospital, Maidstone, UK.<br /><searchLink fieldCode="AU" term="%22Bryant+RJ%22">Bryant RJ</searchLink>; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Surgical Intervention Trials Unit (SITU), University of Oxford, Oxford, UK; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK. Electronic address: richard.bryant@nds.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Lamb+AD%22">Lamb AD</searchLink>; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Department of Urology, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK; Barts Cancer Institute, Queen Mary University of London, London, UK.
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