An alveolar macrophage-targeted ciprofloxacin polymeric prodrug improves survival in a murine model of Klebsiella pneumoniae pneumonia.

Saved in:
Bibliographic Details
Title: An alveolar macrophage-targeted ciprofloxacin polymeric prodrug improves survival in a murine model of Klebsiella pneumoniae pneumonia.
Authors: López CL; Department of Bioengineering, University of Washington, Seattle, Washington, USA., Rerolle G; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA., Snyder S; Department of Bioengineering, University of Washington, Seattle, Washington, USA., Arias O; Department of Bioengineering, University of Washington, Seattle, Washington, USA., Bashmail A; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA., Gonzalez G; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA., Roy D; Department of Bioengineering, University of Washington, Seattle, Washington, USA., Lee B; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA., Snyder JM; Department of Comparative Medicine, University of Washington, Seattle, Washington, USA., Doorn I; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA., Baker SM; Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA., Wright SW; Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Washington, Seattle, Washington, USA., West TE; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA., Skerrett SJ; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA., Stayton PS; Department of Bioengineering, University of Washington, Seattle, Washington, USA.
Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2026 Feb 04; Vol. 70 (2), pp. e0036325. Date of Electronic Publication: 2025 Dec 16.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1098-6596
DOI:10.1128/aac.00363-25