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Adjunctive bright light therapy to enhance continuous positive airway pressure adherence in patients with comorbid major depressive disorder and obstructive sleep apnoea syndrome: study protocol for a randomised sham-controlled trial.

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Title: Adjunctive bright light therapy to enhance continuous positive airway pressure adherence in patients with comorbid major depressive disorder and obstructive sleep apnoea syndrome: study protocol for a randomised sham-controlled trial.
Authors: El Azzaoui H; Le Vinatier Hospital Center, Bron, France.; Université Claude Bernard Lyon 1, CNRS, INSERM, Centre de Recherche en Neurosciences de Lyon CRNL U1028 UMR5292, PSYR2, F-69500, Bron, France, Bron, France.; Linde Homecare,102 bd Edouard Herriot, CS40249 Viriat, F-01006 Bourg en Bresse Cedex, France, Bourg en Bresse, France., Catoire S; Le Vinatier Hospital Center, Bron, France., Lecharpentier H; Le Vinatier Hospital Center, Bron, France., Felician J; Le Vinatier Hospital Center, Bron, France., Grasset O; Linde Homecare,102 bd Edouard Herriot, CS40249 Viriat, F-01006 Bourg en Bresse Cedex, France, Bourg en Bresse, France., Gronfier C; Université Claude Bernard Lyon 1, CNRS, INSERM, Centre de Recherche en Neurosciences de Lyon CRNL, U1028, UMR5292, WAKING, F-69500, Bron, France, Bron, France., Vallet W; Le Vinatier Hospital Center, Bron, France.; Université Claude Bernard Lyon 1, CNRS, INSERM, Centre de Recherche en Neurosciences de Lyon CRNL U1028 UMR5292, PSYR2, F-69500, Bron, France, Bron, France., D'amato T; Le Vinatier Hospital Center, Bron, France.; Université Claude Bernard Lyon 1, CNRS, INSERM, Centre de Recherche en Neurosciences de Lyon CRNL U1028 UMR5292, PSYR2, F-69500, Bron, France, Bron, France., Brunelin J; Le Vinatier Hospital Center, Bron, France jerome.brunelin@ch-le-vinatier.fr.; Université Claude Bernard Lyon 1, CNRS, INSERM, Centre de Recherche en Neurosciences de Lyon CRNL U1028 UMR5292, PSYR2, F-69500, Bron, France, Bron, France.
Source: BMJ open [BMJ Open] 2025 Dec 15; Vol. 15 (12), pp. e108669. Date of Electronic Publication: 2025 Dec 15.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2044-6055
DOI:10.1136/bmjopen-2025-108669