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Coordinate tumor-antigen uptake and dendritic cell activation by chimeric antigen receptors.

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Title: Coordinate tumor-antigen uptake and dendritic cell activation by chimeric antigen receptors.
Authors: Mohammadzadeh Y; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL), 1015 Lausanne, Switzerland.; Agora Cancer Research Center, 1011 Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Switzerland., Gligorovski V; Laboratory of the Physics of Biological Systems, Institute of Physics, EPFL, 1015 Lausanne, Switzerland.; Division of Pulmonary Medicine, Department of Medicine, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), 1011 Lausanne, Switzerland., Egorova O; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL), 1015 Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Switzerland., Casagrande Raffi G; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL), 1015 Lausanne, Switzerland.; Agora Cancer Research Center, 1011 Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Switzerland., van der Schans JJ; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL), 1015 Lausanne, Switzerland.; Agora Cancer Research Center, 1011 Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Switzerland., Ghasemi A; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL), 1015 Lausanne, Switzerland.; Agora Cancer Research Center, 1011 Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Switzerland., Jonas K; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL), 1015 Lausanne, Switzerland.; Agora Cancer Research Center, 1011 Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Switzerland.; Division of Oncology, Department of Internal Medicine, Medical University of Graz, 8036 Graz, Austria., Torchia B; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL), 1015 Lausanne, Switzerland.; Agora Cancer Research Center, 1011 Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Switzerland., Guichard A; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL), 1015 Lausanne, Switzerland.; Agora Cancer Research Center, 1011 Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Switzerland., Marcone R; Agora Cancer Research Center, 1011 Lausanne, Switzerland.; Translational Data Science (TDS) Facility, Swiss Institute of Bioinformatics (SIB), 1011 Lausanne, Switzerland., Martinez-Usatorre A; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL), 1015 Lausanne, Switzerland.; Agora Cancer Research Center, 1011 Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Switzerland., Köck A; Swiss Cancer Center Léman (SCCL), Switzerland.; Department of Oncology, UNIL and CHUV, 1011 Lausanne, Switzerland.; Ludwig Institute for Cancer Research, Lausanne Branch, 1011 Lausanne, Switzerland., Genolet R; Department of Oncology, UNIL and CHUV, 1011 Lausanne, Switzerland.; Ludwig Institute for Cancer Research, Lausanne Branch, 1011 Lausanne, Switzerland., Fournier N; Agora Cancer Research Center, 1011 Lausanne, Switzerland.; Translational Data Science (TDS) Facility, Swiss Institute of Bioinformatics (SIB), 1011 Lausanne, Switzerland., Petrova TV; Swiss Cancer Center Léman (SCCL), Switzerland.; Department of Oncology, UNIL and CHUV, 1011 Lausanne, Switzerland.; Ludwig Institute for Cancer Research, Lausanne Branch, 1011 Lausanne, Switzerland., Speiser DE; Swiss Cancer Center Léman (SCCL), Switzerland.; Department of Oncology, UNIL and CHUV, 1011 Lausanne, Switzerland., Rahi SJ; Laboratory of the Physics of Biological Systems, Institute of Physics, EPFL, 1015 Lausanne, Switzerland., Mansouri N; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL), 1015 Lausanne, Switzerland.; Agora Cancer Research Center, 1011 Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Switzerland.; Division of Pulmonary Medicine, Department of Medicine, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), 1011 Lausanne, Switzerland., De Palma M; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL), 1015 Lausanne, Switzerland.; Agora Cancer Research Center, 1011 Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Switzerland.
Source: Science translational medicine [Sci Transl Med] 2025 Dec 17; Vol. 17 (829), pp. eadq4060. Date of Electronic Publication: 2025 Dec 17.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1946-6242
DOI:10.1126/scitranslmed.adq4060