Lymphodepleting chemotherapy potentiates neoantigen-directed T cell therapy by enhancing antigen presentation.

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Bibliographic Details
Title: Lymphodepleting chemotherapy potentiates neoantigen-directed T cell therapy by enhancing antigen presentation.
Authors: Sagie S; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel; Jusidman Cancer Center, Sheba Medical Center, Ramat Gan 52621, Israel., Babu T; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel., Weller C; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel., Tabachnik C; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel., Livneh I; Rappaport Technion Cancer Research center, The Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525433, Israel; Institute of Pathology, Rambam Health Care Campus, Haifa 3109601, Israel., Quast NP; Department of Statistics, University of Oxford, OX1 3LB Oxford, UK., Gumpert N; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel., Shomuradova A; Sir William Dunn School of Pathology, University of Oxford, OX1 3RE Oxford, UK., Raybould MI; Department of Statistics, University of Oxford, OX1 3LB Oxford, UK., Levy R; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel., Malko D; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel., Alfia A; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel., Ben Lulu T; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel., Alon M; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel., Herrera F; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel., Kutuzov M; Sir William Dunn School of Pathology, University of Oxford, OX1 3RE Oxford, UK., Zerbib M; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot 7610001, Israel., Greenberg P; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel., Wasserman-Bartov T; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel., Benedek G; Faculty of Medicine, Hadassah Hebrew-University Medical Center, Jerusalem 91120, Israel., Levin Y; INCPM, Weizmann Institute of Science, Rehovot 7610001, Israel., Stossel C; Jusidman Cancer Center, Sheba Medical Center, Ramat Gan 52621, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel., Kamer I; Jusidman Cancer Center, Sheba Medical Center, Ramat Gan 52621, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel., Golan T; Jusidman Cancer Center, Sheba Medical Center, Ramat Gan 52621, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel., Oren R; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot 7610001, Israel., Shmueli M; Department of Systems Immunology, Weizmann Institute of Science, Rehovot 7610001, Israel., Bartok O; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel., Bar J; Jusidman Cancer Center, Sheba Medical Center, Ramat Gan 52621, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel., Cohen J; Sharett Institute of Oncology, Hadassah Cancer Research Institute and The Wohl Institute for Translational Medicine, Hadassah-Hebrew University Medical Center, Jerusalem 91120, Israel., Dushek O; Sir William Dunn School of Pathology, University of Oxford, OX1 3RE Oxford, UK., Deane CM; Department of Statistics, University of Oxford, OX1 3LB Oxford, UK., Samuels Y; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address: yardena.samuels@weizmann.ac.il.
Source: Cell reports. Medicine [Cell Rep Med] 2025 Dec 16; Vol. 6 (12), pp. 102506.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2666-3791
DOI:10.1016/j.xcrm.2025.102506