Benefits and risks of antipsychotic discontinuation in people with first and multi-episode psychotic disorders or with schizophrenia: why, when, how and in whom?

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Title: Benefits and risks of antipsychotic discontinuation in people with first and multi-episode psychotic disorders or with schizophrenia: why, when, how and in whom?
Authors: Correll CU; Charité-Universitätsmedizin Berlin, Department of Child and Adolescent Psychiatry, Berlin, Germany. ccorrell@northwell.edu.; German Center for Mental Health (DZPG), partner site Berlin, Berlin, Germany. ccorrell@northwell.edu.; German Center for Child and Adolescent Health (DZKJ), partner site Berlin, Berlin, Germany. ccorrell@northwell.edu.; Einstein Center for Population Diversity (ECPD), Berlin, Germany. ccorrell@northwell.edu.; Northwell, New Hyde Park, NY, USA. ccorrell@northwell.edu.; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Department of Psychiatry and Molecular Medicine, Hempstead, NY, USA. ccorrell@northwell.edu.; The Feinstein Institute for Medical Research, Center for Psychiatric Neuroscience, Northwell Health, New Hyde Park, NY, USA. ccorrell@northwell.edu., Rubio JM; Northwell, New Hyde Park, NY, USA.; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Department of Psychiatry and Molecular Medicine, Hempstead, NY, USA.; The Feinstein Institute for Medical Research, Center for Psychiatric Neuroscience, Northwell Health, New Hyde Park, NY, USA., Kane JM; Northwell, New Hyde Park, NY, USA.; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Department of Psychiatry and Molecular Medicine, Hempstead, NY, USA.; The Feinstein Institute for Medical Research, Center for Psychiatric Neuroscience, Northwell Health, New Hyde Park, NY, USA.
Source: Schizophrenia (Heidelberg, Germany) [Schizophrenia (Heidelb)] 2025 Dec 17; Vol. 11 (1), pp. 151. Date of Electronic Publication: 2025 Dec 17.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Limited Country of Publication: Germany NLM ID: 9918367987006676 Publication Model: Electronic Cited Medium: Internet ISSN: 2754-6993 (Electronic) Linking ISSN: 27546993 NLM ISO Abbreviation: Schizophrenia (Heidelb) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2754-6993
DOI:10.1038/s41537-025-00700-3