View in EDS

Efficacy of isoniazid in paediatric tuberculosis: an individual participant data meta-analysis.

Saved in:
Bibliographic Details
Title: Efficacy of isoniazid in paediatric tuberculosis: an individual participant data meta-analysis.
Authors: Béranger A; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; UCSF Center for Tuberculosis, University of California San Francisco, San Francisco, CA, USA.; Université Paris Cité, INSERM, UMR1343, Pharmacologie et Evaluation des Thérapeutiques chez l'Enfant et la Femme Enceinte, Paris, France.; Réanimation et Soins Intensifs Polyvalents Pédiatriques - SMUR Pédiatrique, AP-HP.Centre - Université de Paris Cité, Hôpital Necker Enfants Malades, Paris, France.; A. Béranger and B.P. Solans are equal contributors to this work and designated as co-first authors., Solans BP; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; UCSF Center for Tuberculosis, University of California San Francisco, San Francisco, CA, USA.; A. Béranger and B.P. Solans are equal contributors to this work and designated as co-first authors., Miyakawa R; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; UCSF Center for Tuberculosis, University of California San Francisco, San Francisco, CA, USA., McIlleron H; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa., Tarning J; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Shah I; Pediatric DR-TB Center of Excellence (State), Department of Pediatric Infectious Diseases, B.J. Wadia Hospital for Children, Mumbai, India., Aruldhas BW; Department of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, India., Mathew BS; Department of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, India., Kwara A; Department of Medicine, College of Medicine, University of Florida, Gainesville, FL, USA., Peloquin CA; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA., Mukherjee A; Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, India., Lodha R; Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, India., Denti P; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa., Capparelli EV; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.; Pediatrics Department, Rady Children's Hospital San Diego, University of California San Diego, La Jolla, CA, USA., Kiser JJ; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz, Aurora, CO, USA., Bekker A; Family Centre for Research with Ubuntu, Department of Paediatric and Child Health, Stellenbosch University, Cape Town, South Africa., Chabala C; Department of Paediatrics and Child Health, School of Medicine, University of Zambia, Lusaka, Zambia.; University Teaching Hospital, Children's Hospital, Lusaka, Zambia., Choo L; Medical Research Council Clinical Trials Unit, University College London, London, UK., Turkova A; Medical Research Council Clinical Trials Unit, University College London, London, UK., Gafar F; Unit of PharmacoTherapy, -Epidemiology and -Economics, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands.; Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.; Respiratory Epidemiology and Clinical Research Unit, Centre for Outcomes Research and Evaluation, Research Institute of the McGill University Health Centre, Montreal, QC, Canada.; McGill International TB Centre, McGill University, Montreal, QC, Canada., Ruslami R; Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.; McGill International TB Centre, McGill University, Montreal, QC, Canada., Nataprawira HM; Division of Pediatric Respirology, Department of Child Health, Hasan Sadikin Hospital, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia., Heysell SK; Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA., Thomas TA; Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA., Velpandian T; Department of Ocular Pharmacology and Pharmacy, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India., Day JN; Department of Clinical Microbiology and Infection, Royal Devon and Exeter University Hospital NHS Trust, Exeter, UK., Bang ND; Pham Ngoc Thach Hospital for Tuberculosis and Lung Disease, Ho Chi Minh City, Vietnam., Dooley K; Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA., Savic RM; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA rada.savic@ucsf.edu.; UCSF Center for Tuberculosis, University of California San Francisco, San Francisco, CA, USA.
Source: The European respiratory journal [Eur Respir J] 2026 Mar 05; Vol. 67 (3). Date of Electronic Publication: 2026 Mar 05 (Print Publication: 2026).
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: European Respiratory Society Country of Publication: England NLM ID: 8803460 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1399-3003 (Electronic) Linking ISSN: 09031936 NLM ISO Abbreviation: Eur Respir J Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41412716
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Efficacy of isoniazid in paediatric tuberculosis: an individual participant data meta-analysis.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Béranger+A%22">Béranger A</searchLink>; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; UCSF Center for Tuberculosis, University of California San Francisco, San Francisco, CA, USA.; Université Paris Cité, INSERM, UMR1343, Pharmacologie et Evaluation des Thérapeutiques chez l'Enfant et la Femme Enceinte, Paris, France.; Réanimation et Soins Intensifs Polyvalents Pédiatriques - SMUR Pédiatrique, AP-HP.Centre - Université de Paris Cité, Hôpital Necker Enfants Malades, Paris, France.; A. Béranger and B.P. Solans are equal contributors to this work and designated as co-first authors.<br /><searchLink fieldCode="AU" term="%22Solans+BP%22">Solans BP</searchLink>; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; UCSF Center for Tuberculosis, University of California San Francisco, San Francisco, CA, USA.; A. Béranger and B.P. Solans are equal contributors to this work and designated as co-first authors.<br /><searchLink fieldCode="AU" term="%22Miyakawa+R%22">Miyakawa R</searchLink>; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; UCSF Center for Tuberculosis, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22McIlleron+H%22">McIlleron H</searchLink>; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Tarning+J%22">Tarning J</searchLink>; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Shah+I%22">Shah I</searchLink>; Pediatric DR-TB Center of Excellence (State), Department of Pediatric Infectious Diseases, B.J. Wadia Hospital for Children, Mumbai, India.<br /><searchLink fieldCode="AU" term="%22Aruldhas+BW%22">Aruldhas BW</searchLink>; Department of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22Mathew+BS%22">Mathew BS</searchLink>; Department of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22Kwara+A%22">Kwara A</searchLink>; Department of Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Peloquin+CA%22">Peloquin CA</searchLink>; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Mukherjee+A%22">Mukherjee A</searchLink>; Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, India.<br /><searchLink fieldCode="AU" term="%22Lodha+R%22">Lodha R</searchLink>; Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, India.<br /><searchLink fieldCode="AU" term="%22Denti+P%22">Denti P</searchLink>; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Capparelli+EV%22">Capparelli EV</searchLink>; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.; Pediatrics Department, Rady Children's Hospital San Diego, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kiser+JJ%22">Kiser JJ</searchLink>; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Bekker+A%22">Bekker A</searchLink>; Family Centre for Research with Ubuntu, Department of Paediatric and Child Health, Stellenbosch University, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Chabala+C%22">Chabala C</searchLink>; Department of Paediatrics and Child Health, School of Medicine, University of Zambia, Lusaka, Zambia.; University Teaching Hospital, Children's Hospital, Lusaka, Zambia.<br /><searchLink fieldCode="AU" term="%22Choo+L%22">Choo L</searchLink>; Medical Research Council Clinical Trials Unit, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Turkova+A%22">Turkova A</searchLink>; Medical Research Council Clinical Trials Unit, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Gafar+F%22">Gafar F</searchLink>; Unit of PharmacoTherapy, -Epidemiology and -Economics, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands.; Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.; Respiratory Epidemiology and Clinical Research Unit, Centre for Outcomes Research and Evaluation, Research Institute of the McGill University Health Centre, Montreal, QC, Canada.; McGill International TB Centre, McGill University, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Ruslami+R%22">Ruslami R</searchLink>; Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.; McGill International TB Centre, McGill University, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Nataprawira+HM%22">Nataprawira HM</searchLink>; Division of Pediatric Respirology, Department of Child Health, Hasan Sadikin Hospital, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.<br /><searchLink fieldCode="AU" term="%22Heysell+SK%22">Heysell SK</searchLink>; Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+TA%22">Thomas TA</searchLink>; Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Velpandian+T%22">Velpandian T</searchLink>; Department of Ocular Pharmacology and Pharmacy, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.<br /><searchLink fieldCode="AU" term="%22Day+JN%22">Day JN</searchLink>; Department of Clinical Microbiology and Infection, Royal Devon and Exeter University Hospital NHS Trust, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22Bang+ND%22">Bang ND</searchLink>; Pham Ngoc Thach Hospital for Tuberculosis and Lung Disease, Ho Chi Minh City, Vietnam.<br /><searchLink fieldCode="AU" term="%22Dooley+K%22">Dooley K</searchLink>; Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Savic+RM%22">Savic RM</searchLink>; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA rada.savic@ucsf.edu.; UCSF Center for Tuberculosis, University of California San Francisco, San Francisco, CA, USA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%228803460%22">The European respiratory journal</searchLink> [Eur Respir J] 2026 Mar 05; Vol. 67 (3). <i>Date of Electronic Publication: </i>2026 Mar 05 (<i>Print Publication: </i>2026).
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Meta-Analysis
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22European+Respiratory+Society%22">European Respiratory Society </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8803460 <i>Publication Model: </i>Electronic-Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1399-3003 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209031936%22">09031936 </searchLink><i>NLM ISO Abbreviation: </i>Eur Respir J <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41412716
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1183/13993003.01046-2025
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Efficacy of isoniazid in paediatric tuberculosis: an individual participant data meta-analysis.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Béranger A
      – PersonEntity:
          Name:
            NameFull: Solans BP
      – PersonEntity:
          Name:
            NameFull: Miyakawa R
      – PersonEntity:
          Name:
            NameFull: McIlleron H
      – PersonEntity:
          Name:
            NameFull: Tarning J
      – PersonEntity:
          Name:
            NameFull: Shah I
      – PersonEntity:
          Name:
            NameFull: Aruldhas BW
      – PersonEntity:
          Name:
            NameFull: Mathew BS
      – PersonEntity:
          Name:
            NameFull: Kwara A
      – PersonEntity:
          Name:
            NameFull: Peloquin CA
      – PersonEntity:
          Name:
            NameFull: Mukherjee A
      – PersonEntity:
          Name:
            NameFull: Lodha R
      – PersonEntity:
          Name:
            NameFull: Denti P
      – PersonEntity:
          Name:
            NameFull: Capparelli EV
      – PersonEntity:
          Name:
            NameFull: Kiser JJ
      – PersonEntity:
          Name:
            NameFull: Bekker A
      – PersonEntity:
          Name:
            NameFull: Chabala C
      – PersonEntity:
          Name:
            NameFull: Choo L
      – PersonEntity:
          Name:
            NameFull: Turkova A
      – PersonEntity:
          Name:
            NameFull: Gafar F
      – PersonEntity:
          Name:
            NameFull: Ruslami R
      – PersonEntity:
          Name:
            NameFull: Nataprawira HM
      – PersonEntity:
          Name:
            NameFull: Heysell SK
      – PersonEntity:
          Name:
            NameFull: Thomas TA
      – PersonEntity:
          Name:
            NameFull: Velpandian T
      – PersonEntity:
          Name:
            NameFull: Day JN
      – PersonEntity:
          Name:
            NameFull: Bang ND
      – PersonEntity:
          Name:
            NameFull: Dooley K
      – PersonEntity:
          Name:
            NameFull: Savic RM
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 05
              M: 03
              Text: 2026 Mar 05
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1399-3003
          Numbering:
            – Type: volume
              Value: 67
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: The European respiratory journal
              Type: main
ResultId 1