Protective anti-fibrotic effect of liraglutide and Pirfenidone combination therapy on liver fibrosis in rats: effects on autophagy and NLRP3 inflammasome.
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| Title: | Protective anti-fibrotic effect of liraglutide and Pirfenidone combination therapy on liver fibrosis in rats: effects on autophagy and NLRP3 inflammasome. |
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| Authors: | Yousefi Z; Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Metabolic Disorders Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran., Rajabi R; Oncopathology Research Center, Iran University of Medical Sciences, Tehran, Iran., Karima S; Department of Clinical Biochemistry, School of Medicine, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran., Nourbakhsh M; Metabolic Disorders Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. Nourbakhsh.m@iums.ac.ir.; Department of Clinical Biochemistry, School of Medicine, Iran University of Medical Sciences, Tehran, 1449614535, Iran. Nourbakhsh.m@iums.ac.ir., Lotfi AS; Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, Jalal Ale Ahmad, Nasr, P.O. Box: 14115-111, Tehran, Iran. lotfi_ab@modares.ac.ir.; Iran University of Medical Sciences, Hemmat Highway, P.O. Box: 1419614535, Tehran, Iran. lotfi_ab@modares.ac.ir. |
| Source: | BMC gastroenterology [BMC Gastroenterol] 2025 Dec 18; Vol. 26 (1), pp. 57. Date of Electronic Publication: 2025 Dec 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 100968547 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-230X (Electronic) Linking ISSN: 1471230X NLM ISO Abbreviation: BMC Gastroenterol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41413484 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Protective anti-fibrotic effect of liraglutide and Pirfenidone combination therapy on liver fibrosis in rats: effects on autophagy and NLRP3 inflammasome. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Yousefi+Z%22">Yousefi Z</searchLink>; Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Metabolic Disorders Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Rajabi+R%22">Rajabi R</searchLink>; Oncopathology Research Center, Iran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Karima+S%22">Karima S</searchLink>; Department of Clinical Biochemistry, School of Medicine, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Nourbakhsh+M%22">Nourbakhsh M</searchLink>; Metabolic Disorders Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. Nourbakhsh.m@iums.ac.ir.; Department of Clinical Biochemistry, School of Medicine, Iran University of Medical Sciences, Tehran, 1449614535, Iran. Nourbakhsh.m@iums.ac.ir.<br /><searchLink fieldCode="AU" term="%22Lotfi+AS%22">Lotfi AS</searchLink>; Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, Jalal Ale Ahmad, Nasr, P.O. Box: 14115-111, Tehran, Iran. lotfi&#95;ab@modares.ac.ir.; Iran University of Medical Sciences, Hemmat Highway, P.O. Box: 1419614535, Tehran, Iran. lotfi&#95;ab@modares.ac.ir. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22100968547%22">BMC gastroenterology</searchLink> [BMC Gastroenterol] 2025 Dec 18; Vol. 26 (1), pp. 57. <i>Date of Electronic Publication: </i>2025 Dec 18. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100968547 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-230X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221471230X%22">1471230X </searchLink><i>NLM ISO Abbreviation: </i>BMC Gastroenterol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41413484 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s12876-025-04545-z Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 57 Titles: – TitleFull: Protective anti-fibrotic effect of liraglutide and Pirfenidone combination therapy on liver fibrosis in rats: effects on autophagy and NLRP3 inflammasome. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Yousefi Z – PersonEntity: Name: NameFull: Rajabi R – PersonEntity: Name: NameFull: Karima S – PersonEntity: Name: NameFull: Nourbakhsh M – PersonEntity: Name: NameFull: Lotfi AS IsPartOfRelationships: – BibEntity: Dates: – D: 18 M: 12 Text: 2025 Dec 18 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1471-230X Numbering: – Type: volume Value: 26 – Type: issue Value: 1 Titles: – TitleFull: BMC gastroenterology Type: main |
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