Biomimetic and microenvironment-adaptive nanoplatform potentiates photodynamic therapy of rheumatoid arthritis via H2S-Modulated oxygen metabolism.

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Title: Biomimetic and microenvironment-adaptive nanoplatform potentiates photodynamic therapy of rheumatoid arthritis via H2S-Modulated oxygen metabolism.
Authors: Zhang X; School of Pharmacy and State Key Laboratory of Mechanism and Quality of Chinese Medicine, Macau University of Science and Technology, Macao, 999078, China., Meng S; School of Pharmacy and State Key Laboratory of Mechanism and Quality of Chinese Medicine, Macau University of Science and Technology, Macao, 999078, China., Xiao Y; School of Pharmacy and State Key Laboratory of Mechanism and Quality of Chinese Medicine, Macau University of Science and Technology, Macao, 999078, China., Liu Y; School of Pharmacy and State Key Laboratory of Mechanism and Quality of Chinese Medicine, Macau University of Science and Technology, Macao, 999078, China., Tang Z; School of Pharmacy and State Key Laboratory of Mechanism and Quality of Chinese Medicine, Macau University of Science and Technology, Macao, 999078, China., Li A; School of Pharmacy and State Key Laboratory of Mechanism and Quality of Chinese Medicine, Macau University of Science and Technology, Macao, 999078, China., Wu K; School of Pharmacy and State Key Laboratory of Mechanism and Quality of Chinese Medicine, Macau University of Science and Technology, Macao, 999078, China., Cheng C; College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu, 610065, China., Mao Z; MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, Zhejiang, 310027, China., Guo H; School of Pharmacy and State Key Laboratory of Mechanism and Quality of Chinese Medicine, Macau University of Science and Technology, Macao, 999078, China. Electronic address: guoh37@mail.sysu.edu.cn., Zhu YZ; School of Pharmacy and State Key Laboratory of Mechanism and Quality of Chinese Medicine, Macau University of Science and Technology, Macao, 999078, China. Electronic address: yzzhu@must.edu.mo., Wang X; School of Pharmacy and State Key Laboratory of Mechanism and Quality of Chinese Medicine, Macau University of Science and Technology, Macao, 999078, China. Electronic address: xilwang@must.edu.mo.
Source: Biomaterials [Biomaterials] 2026 Jun; Vol. 329, pp. 123926. Date of Electronic Publication: 2025 Dec 15.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8100316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5905 (Electronic) Linking ISSN: 01429612 NLM ISO Abbreviation: Biomaterials Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1878-5905
DOI:10.1016/j.biomaterials.2025.123926