Antinociceptive role of IL-10/STAT3 signaling in trigeminal neuropathic pain male rat model through Pomc and β-endorphin.

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Title: Antinociceptive role of IL-10/STAT3 signaling in trigeminal neuropathic pain male rat model through Pomc and β-endorphin.
Authors: Perdana LP; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Sciences, Tokushima University, Tokushima 770-8504, Japan., Fabillar J Jr; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Sciences, Tokushima University, Tokushima 770-8504, Japan; College of Dentistry, Southwestern University PHINMA, Cebu City 6000, Philippines., Arini DS; Department of Oral Health Science and Social Welfare, Graduate School of Oral Sciences, Tokushima University, Tokushima 770-8504, Japan., Raman S; Department of Neural and Pain Science, School of Dentistry, University of Maryland, MD 21201, USA., Raju R; Section on Craniofacial Genetic Disorders, Eunice Kennedy Shriver, National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), MD 20892, USA., Ikutame D; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Sciences, Tokushima University, Tokushima 770-8504, Japan., Oshima M; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Sciences, Tokushima University, Tokushima 770-8504, Japan., Miyoshi K; Department of Innovative Dental Education and Bioscience, Graduate School of Biomedical Sciences, Tokushima University, Tokushima 770-8504, Japan., Matsuka Y; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Sciences, Tokushima University, Tokushima 770-8504, Japan. Electronic address: matsuka@tokushima-u.ac.jp.
Source: Neuroscience letters [Neurosci Lett] 2026 Feb 26; Vol. 873, pp. 138492. Date of Electronic Publication: 2025 Dec 18.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Scientific Publishers Ireland Country of Publication: Ireland NLM ID: 7600130 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7972 (Electronic) Linking ISSN: 03043940 NLM ISO Abbreviation: Neurosci Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1872-7972
DOI:10.1016/j.neulet.2025.138492