TRP canonical 4 and/or 5 channel inhibition reduces aversion- and increases reward-responding in chronically stressed mice.

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Title: TRP canonical 4 and/or 5 channel inhibition reduces aversion- and increases reward-responding in chronically stressed mice.
Authors: Poggi G; Preclinical Laboratory, Department of Adult Psychiatry and Psychotherapy, University Hospital of Psychiatry and University of Zurich, Zurich, Switzerland., Queisser D; Preclinical Laboratory, Department of Adult Psychiatry and Psychotherapy, University Hospital of Psychiatry and University of Zurich, Zurich, Switzerland., Senn A; Preclinical Laboratory, Department of Adult Psychiatry and Psychotherapy, University Hospital of Psychiatry and University of Zurich, Zurich, Switzerland., Sigrist H; Preclinical Laboratory, Department of Adult Psychiatry and Psychotherapy, University Hospital of Psychiatry and University of Zurich, Zurich, Switzerland., Kúkeľová D; Preclinical Laboratory, Department of Adult Psychiatry and Psychotherapy, University Hospital of Psychiatry and University of Zurich, Zurich, Switzerland., Madur L; Preclinical Laboratory, Department of Adult Psychiatry and Psychotherapy, University Hospital of Psychiatry and University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, ETH and University of Zurich, Zurich, Switzerland., Cuomo-Haymour N; Preclinical Laboratory, Department of Adult Psychiatry and Psychotherapy, University Hospital of Psychiatry and University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, ETH and University of Zurich, Zurich, Switzerland., Robert M; Preclinical Laboratory, Department of Adult Psychiatry and Psychotherapy, University Hospital of Psychiatry and University of Zurich, Zurich, Switzerland., Schmid S; Preclinical Laboratory, Department of Adult Psychiatry and Psychotherapy, University Hospital of Psychiatry and University of Zurich, Zurich, Switzerland., Portalés A; Preclinical Laboratory, Department of Adult Psychiatry and Psychotherapy, University Hospital of Psychiatry and University of Zurich, Zurich, Switzerland., Simard S; Department of Psychiatry, McGill University, Montreal, Quebec, Canada., Mechawar N; Department of Psychiatry, McGill University, Montreal, Quebec, Canada., Hengerer B; Department of CNS Diseases Research, Boehringer Ingelheim Pharma GmbH & Co KG, Biberach, Germany., Just S; Department of CNS Diseases Research, Boehringer Ingelheim Pharma GmbH & Co KG, Biberach, Germany., Pryce CR; Preclinical Laboratory, Department of Adult Psychiatry and Psychotherapy, University Hospital of Psychiatry and University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, ETH and University of Zurich, Zurich, Switzerland.
Source: British journal of pharmacology [Br J Pharmacol] 2026 May; Vol. 183 (9), pp. 2139-2165. Date of Electronic Publication: 2025 Dec 21.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5381
DOI:10.1111/bph.70305