TMEM120A maintains adipose tissue lipid homeostasis through ER CoA channeling.

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Title: TMEM120A maintains adipose tissue lipid homeostasis through ER CoA channeling.
Authors: Cho YK; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea., Lee J; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea., Jeong YL; Department of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang, Republic of Korea., Shim M; College of Pharmacy, Chung-Ang University, Seoul, Republic of Korea., Mai XL; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea., Seomoon C; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea., Jung CW; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea., Choi YH; Department of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang, Republic of Korea., Namgoong S; Department of Plastic Surgery, Korea University College of Medicine, Seoul, Republic of Korea., Jung YS; College of Pharmacy, Pusan National University, Busan, Republic of Korea., Kwon SW; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea., Lee J; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea., Seong JK; Korea Mouse Phenotyping (KMPC), and Laboratory of Developmental Biology and Genomics, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea., Park S; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea., Mottillo EP; Department of Physiology, Wayne State University School of Medicine, Detroit, MI, USA., Granneman JG; Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI, USA., Lee DK; College of Pharmacy, Chung-Ang University, Seoul, Republic of Korea. leedk@cau.ac.kr., Kim JK; Department of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang, Republic of Korea. blkimjk@postech.ac.kr.; Institute for Convergence Research and Education in Advanced Technology, Yonsei University, Seoul, South Korea. blkimjk@postech.ac.kr., Lee YH; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea. yunhee.lee@snu.ac.kr.
Source: Nature communications [Nat Commun] 2025 Dec 21; Vol. 17 (1), pp. 1113. Date of Electronic Publication: 2025 Dec 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-67870-7