FK506 binding protein 12.6-mediated inhibition of sperm-specific calcineurin is essential for FK506-induced male infertility by disturbing the homeostasis of calcium and mitochondria.
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| Title: | FK506 binding protein 12.6-mediated inhibition of sperm-specific calcineurin is essential for FK506-induced male infertility by disturbing the homeostasis of calcium and mitochondria. |
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| Authors: | Xiao YF; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China. xyf.84@163.com.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China. xyf.84@163.com., Yang SF; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China.; School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330031, People's Republic of China., Huang SA; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China.; School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330031, People's Republic of China., Zeng ZX; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China., Gong LN; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China., Xie L; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.; Jiangxi Provincial People's Hospital, the First Affiliated Hospital of Nanchang Medical College, Nanchang, 330031, People's Republic of China., Wang LF; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China., Guan XH; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China., Jiang MX; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China., Qian YS; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China., Deng KY; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China. dky@ncu.edu.cn.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China. dky@ncu.edu.cn.; School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330031, People's Republic of China. dky@ncu.edu.cn., Xin HB; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China. xinhb@ncu.edu.cn.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China. xinhb@ncu.edu.cn.; School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330031, People's Republic of China. xinhb@ncu.edu.cn. |
| Source: | Molecular biomedicine [Mol Biomed] 2025 Dec 22; Vol. 6 (1), pp. 149. Date of Electronic Publication: 2025 Dec 22. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Springer Singapore Country of Publication: Singapore NLM ID: 9918283581406676 Publication Model: Electronic Cited Medium: Internet ISSN: 2662-8651 (Electronic) Linking ISSN: 26628651 NLM ISO Abbreviation: Mol Biomed Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41428164 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: FK506 binding protein 12.6-mediated inhibition of sperm-specific calcineurin is essential for FK506-induced male infertility by disturbing the homeostasis of calcium and mitochondria. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Xiao+YF%22">Xiao YF</searchLink>; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China. xyf.84@163.com.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China. xyf.84@163.com.<br /><searchLink fieldCode="AU" term="%22Yang+SF%22">Yang SF</searchLink>; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China.; School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330031, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Huang+SA%22">Huang SA</searchLink>; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China.; School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330031, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zeng+ZX%22">Zeng ZX</searchLink>; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Gong+LN%22">Gong LN</searchLink>; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xie+L%22">Xie L</searchLink>; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.; Jiangxi Provincial People's Hospital, the First Affiliated Hospital of Nanchang Medical College, Nanchang, 330031, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+LF%22">Wang LF</searchLink>; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Guan+XH%22">Guan XH</searchLink>; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Jiang+MX%22">Jiang MX</searchLink>; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Qian+YS%22">Qian YS</searchLink>; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Deng+KY%22">Deng KY</searchLink>; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China. dky@ncu.edu.cn.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China. dky@ncu.edu.cn.; School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330031, People's Republic of China. dky@ncu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Xin+HB%22">Xin HB</searchLink>; National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China. xinhb@ncu.edu.cn.; Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Nanchang, People's Republic of China. xinhb@ncu.edu.cn.; School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330031, People's Republic of China. xinhb@ncu.edu.cn. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229918283581406676%22">Molecular biomedicine</searchLink> [Mol Biomed] 2025 Dec 22; Vol. 6 (1), pp. 149. <i>Date of Electronic Publication: </i>2025 Dec 22. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Singapore%22">Springer Singapore </searchLink><i>Country of Publication: </i>Singapore <i>NLM ID: </i>9918283581406676 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2662-8651 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226628651%22">26628651 </searchLink><i>NLM ISO Abbreviation: </i>Mol Biomed <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41428164 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s43556-025-00391-3 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 149 Titles: – TitleFull: FK506 binding protein 12.6-mediated inhibition of sperm-specific calcineurin is essential for FK506-induced male infertility by disturbing the homeostasis of calcium and mitochondria. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Xiao YF – PersonEntity: Name: NameFull: Yang SF – PersonEntity: Name: NameFull: Huang SA – PersonEntity: Name: NameFull: Zeng ZX – PersonEntity: Name: NameFull: Gong LN – PersonEntity: Name: NameFull: Xie L – PersonEntity: Name: NameFull: Wang LF – PersonEntity: Name: NameFull: Guan XH – PersonEntity: Name: NameFull: Jiang MX – PersonEntity: Name: NameFull: Qian YS – PersonEntity: Name: NameFull: Deng KY – PersonEntity: Name: NameFull: Xin HB IsPartOfRelationships: – BibEntity: Dates: – D: 22 M: 12 Text: 2025 Dec 22 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2662-8651 Numbering: – Type: volume Value: 6 – Type: issue Value: 1 Titles: – TitleFull: Molecular biomedicine Type: main |
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