Schwann cell Lrp1 deletion drives trigeminal neuron sensitization and orofacial pain by modulating mitochondrial function and TRPV1/TRPA1 activity.
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| Title: | Schwann cell Lrp1 deletion drives trigeminal neuron sensitization and orofacial pain by modulating mitochondrial function and TRPV1/TRPA1 activity. |
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| Authors: | Gong Z; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA.; Pain Research Center, Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, 10010, USA., Zhang M; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA.; Pain Research Center, Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, 10010, USA., Liu N; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA.; Pain Research Center, Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, 10010, USA., Asam K; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA., Martellucci S; Department of Anesthesiology, University of California San Diego, San Diego, CA, 92093, USA., Aouizerat B; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA., Campana W; Department of Anesthesiology, University of California San Diego, San Diego, CA, 92093, USA.; San Diego VA Health Care System, San Diego, CA, 92161, USA.; Program in Neurosciences, University of California San Diego, San Diego, CA, 92093, USA., Ye Y; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA. yy22@nyu.edu.; Pain Research Center, Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, 10010, USA. yy22@nyu.edu.; Department of Biomedical Engineering, Tandon School of Engineering, New York University, 433 1st Ave, Room 708, New York, NY, 10010, USA. yy22@nyu.edu. |
| Source: | The journal of headache and pain [J Headache Pain] 2025 Dec 22; Vol. 26 (1), pp. 290. Date of Electronic Publication: 2025 Dec 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 100940562 Publication Model: Electronic Cited Medium: Internet ISSN: 1129-2377 (Electronic) Linking ISSN: 11292369 NLM ISO Abbreviation: J Headache Pain Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1129-2377 |
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| DOI: | 10.1186/s10194-025-02250-6 |
