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Schwann cell Lrp1 deletion drives trigeminal neuron sensitization and orofacial pain by modulating mitochondrial function and TRPV1/TRPA1 activity.

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Title: Schwann cell Lrp1 deletion drives trigeminal neuron sensitization and orofacial pain by modulating mitochondrial function and TRPV1/TRPA1 activity.
Authors: Gong Z; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA.; Pain Research Center, Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, 10010, USA., Zhang M; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA.; Pain Research Center, Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, 10010, USA., Liu N; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA.; Pain Research Center, Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, 10010, USA., Asam K; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA., Martellucci S; Department of Anesthesiology, University of California San Diego, San Diego, CA, 92093, USA., Aouizerat B; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA., Campana W; Department of Anesthesiology, University of California San Diego, San Diego, CA, 92093, USA.; San Diego VA Health Care System, San Diego, CA, 92161, USA.; Program in Neurosciences, University of California San Diego, San Diego, CA, 92093, USA., Ye Y; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA. yy22@nyu.edu.; Pain Research Center, Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, 10010, USA. yy22@nyu.edu.; Department of Biomedical Engineering, Tandon School of Engineering, New York University, 433 1st Ave, Room 708, New York, NY, 10010, USA. yy22@nyu.edu.
Source: The journal of headache and pain [J Headache Pain] 2025 Dec 22; Vol. 26 (1), pp. 290. Date of Electronic Publication: 2025 Dec 22.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100940562 Publication Model: Electronic Cited Medium: Internet ISSN: 1129-2377 (Electronic) Linking ISSN: 11292369 NLM ISO Abbreviation: J Headache Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Schwann cell Lrp1 deletion drives trigeminal neuron sensitization and orofacial pain by modulating mitochondrial function and TRPV1/TRPA1 activity.
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  Data: <searchLink fieldCode="AU" term="%22Gong+Z%22">Gong Z</searchLink>; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA.; Pain Research Center, Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, 10010, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+M%22">Zhang M</searchLink>; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA.; Pain Research Center, Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, 10010, USA.<br /><searchLink fieldCode="AU" term="%22Liu+N%22">Liu N</searchLink>; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA.; Pain Research Center, Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, 10010, USA.<br /><searchLink fieldCode="AU" term="%22Asam+K%22">Asam K</searchLink>; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA.<br /><searchLink fieldCode="AU" term="%22Martellucci+S%22">Martellucci S</searchLink>; Department of Anesthesiology, University of California San Diego, San Diego, CA, 92093, USA.<br /><searchLink fieldCode="AU" term="%22Aouizerat+B%22">Aouizerat B</searchLink>; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA.<br /><searchLink fieldCode="AU" term="%22Campana+W%22">Campana W</searchLink>; Department of Anesthesiology, University of California San Diego, San Diego, CA, 92093, USA.; San Diego VA Health Care System, San Diego, CA, 92161, USA.; Program in Neurosciences, University of California San Diego, San Diego, CA, 92093, USA.<br /><searchLink fieldCode="AU" term="%22Ye+Y%22">Ye Y</searchLink>; Translational Research Center, College of Dentistry, New York University, New York, NY, 10010, USA. yy22@nyu.edu.; Pain Research Center, Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, 10010, USA. yy22@nyu.edu.; Department of Biomedical Engineering, Tandon School of Engineering, New York University, 433 1st Ave, Room 708, New York, NY, 10010, USA. yy22@nyu.edu.
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  Data: <searchLink fieldCode="JN" term="%22100940562%22">The journal of headache and pain</searchLink> [J Headache Pain] 2025 Dec 22; Vol. 26 (1), pp. 290. <i>Date of Electronic Publication: </i>2025 Dec 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100940562 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1129-2377 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211292369%22">11292369 </searchLink><i>NLM ISO Abbreviation: </i>J Headache Pain <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s10194-025-02250-6
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              Text: 2025 Dec 22
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