Leukemia-driven expansion of type 3 innate lymphoid cell facilitates a pro-tumoral microenvironment in acute myeloid leukemia.

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Title: Leukemia-driven expansion of type 3 innate lymphoid cell facilitates a pro-tumoral microenvironment in acute myeloid leukemia.
Authors: Dinh TTT; Biomedical Sciences Graduate Program, The Ohio State University, Columbus, OH, USA.; The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA., Lordo MR; Biomedical Sciences Graduate Program, The Ohio State University, Columbus, OH, USA.; The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.; The Medical Scientist Training Program, The Ohio State University, Columbus, OH, USA., Zhang AY; Biomedical Sciences Graduate Program, The Ohio State University, Columbus, OH, USA.; The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.; The Medical Scientist Training Program, The Ohio State University, Columbus, OH, USA., Goda C; Department of Internal Medicine, University of Utah Health, Salt Lake City, UT, USA., Shilo N; The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA., Altynova E; The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA., Ruesch M; Biomedical Sciences Graduate Program, The Ohio State University, Columbus, OH, USA.; The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.; The Medical Scientist Training Program, The Ohio State University, Columbus, OH, USA., Kronen P; The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA., Broughton M; The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA., Jeremy E; Biomedical Sciences Graduate Program, The Ohio State University, Columbus, OH, USA.; The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.; The Medical Scientist Training Program, The Ohio State University, Columbus, OH, USA., Sellers VL; The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA., Zhang X; Department of Biomedical Informatics, The Ohio State University, Columbus, OH, USA., Larkin KT; The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Collins PL; The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.; Department of Microbial Infection and Immunity, Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, OH, USA., Dorrance AM; Department of Internal Medicine, University of Utah Health, Salt Lake City, UT, USA., Freud AG; The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.; Department of Pathology, The Ohio State University, Columbus, OH, USA., Oakes CC; The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.; Department of Biomedical Informatics, The Ohio State University, Columbus, OH, USA.; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Mundy-Bosse BL; The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA. bethany.mundy@osumc.edu.; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA. bethany.mundy@osumc.edu.; Department of Microbial Infection and Immunity, Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, OH, USA. bethany.mundy@osumc.edu.
Source: Leukemia [Leukemia] 2026 Feb; Vol. 40 (2), pp. 325-338. Date of Electronic Publication: 2025 Dec 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5551
DOI:10.1038/s41375-025-02829-7