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Activities of the Novel Bacterial Topoisomerase Inhibitor OSUAB-0284 against the Biothreat Pathogen Bacillus anthracis and Its Type II Topoisomerases.

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Bibliographic Details
Title:	Activities of the Novel Bacterial Topoisomerase Inhibitor OSUAB-0284 against the Biothreat Pathogen Bacillus anthracis and Its Type II Topoisomerases.
Authors:	Mann CA; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States., Halasohoris SA; Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Fort Detrick, Maryland 21702, United States., Gray AM; Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Fort Detrick, Maryland 21702, United States., Chua J; Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Fort Detrick, Maryland 21702, United States., Spencer JL; Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Fort Detrick, Maryland 21702, United States., Curry BJ; Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Fort Detrick, Maryland 21702, United States., Babyak AL; Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Fort Detrick, Maryland 21702, United States., Klimko CP; Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Fort Detrick, Maryland 21702, United States., Cote CK; Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Fort Detrick, Maryland 21702, United States., West JS; Division of Medicinal Chemistry and Pharmacognosy, The Ohio State University College of Pharmacy, Columbus, Ohio 43210, United States., Mitton-Fry MJ; Division of Medicinal Chemistry and Pharmacognosy, The Ohio State University College of Pharmacy, Columbus, Ohio 43210, United States., Meinig JM; Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Fort Detrick, Maryland 21702, United States., Osheroff N; Departments of Biochemistry and Medicine (Hematology/Oncology), Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States.
Source:	ACS infectious diseases [ACS Infect Dis] 2026 Jan 09; Vol. 12 (1), pp. 363-375. Date of Electronic Publication: 2025 Dec 22.
Publication Type:	Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info:	Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE
Database:	MEDLINE Ultimate

Description
ISSN:	2373-8227
DOI:	10.1021/acsinfecdis.5c00860