Ferroptosis is a novel pathogenic mechanism of FDXR-related disease via disruption of the NRF2 pathway.
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| Title: | Ferroptosis is a novel pathogenic mechanism of FDXR-related disease via disruption of the NRF2 pathway. |
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| Authors: | Campbell T; Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; College of Medicine, University of Cincinnati, Cincinnati, OH, USA., Slone J; Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; College of Medicine, University of Cincinnati, Cincinnati, OH, USA., Vu J; Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA., Liu W; Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA., Yang L; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, Xiangya Hospital; Central South University, Changsha, China., Dourson A; Department of Anesthesia, Division of Pain Management, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Queme LF; Department of Anesthesia, Division of Pain Management, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Biomedical Sciences, University of New England College of Osteopathic Medicine, Biddeford, ME, USA., Jankowski MP; College of Medicine, University of Cincinnati, Cincinnati, OH, USA.; Department of Anesthesia, Division of Pain Management, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Huang T; Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA. taosheng.huang@gmail.com.; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. taosheng.huang@gmail.com.; College of Medicine, University of Cincinnati, Cincinnati, OH, USA. taosheng.huang@gmail.com.; Institute of Medical Genetics & Genomics, Fudan University, 1st Floor, Building B, Suite 1027, Research Building 2, No. 131 Dong'an Road, Xuhui District, Shanghai, China. taosheng.huang@gmail.com. |
| Source: | Cell death discovery [Cell Death Discov] 2025 Dec 23; Vol. 11 (1), pp. 563. Date of Electronic Publication: 2025 Dec 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2058-7716 |
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| DOI: | 10.1038/s41420-025-02840-y |
