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Ferroptosis is a novel pathogenic mechanism of FDXR-related disease via disruption of the NRF2 pathway.

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Title: Ferroptosis is a novel pathogenic mechanism of FDXR-related disease via disruption of the NRF2 pathway.
Authors: Campbell T; Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; College of Medicine, University of Cincinnati, Cincinnati, OH, USA., Slone J; Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; College of Medicine, University of Cincinnati, Cincinnati, OH, USA., Vu J; Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA., Liu W; Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA., Yang L; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, Xiangya Hospital; Central South University, Changsha, China., Dourson A; Department of Anesthesia, Division of Pain Management, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Queme LF; Department of Anesthesia, Division of Pain Management, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Biomedical Sciences, University of New England College of Osteopathic Medicine, Biddeford, ME, USA., Jankowski MP; College of Medicine, University of Cincinnati, Cincinnati, OH, USA.; Department of Anesthesia, Division of Pain Management, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Huang T; Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA. taosheng.huang@gmail.com.; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. taosheng.huang@gmail.com.; College of Medicine, University of Cincinnati, Cincinnati, OH, USA. taosheng.huang@gmail.com.; Institute of Medical Genetics & Genomics, Fudan University, 1st Floor, Building B, Suite 1027, Research Building 2, No. 131 Dong'an Road, Xuhui District, Shanghai, China. taosheng.huang@gmail.com.
Source: Cell death discovery [Cell Death Discov] 2025 Dec 23; Vol. 11 (1), pp. 563. Date of Electronic Publication: 2025 Dec 23.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Ferroptosis is a novel pathogenic mechanism of FDXR-related disease via disruption of the NRF2 pathway.
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  Data: <searchLink fieldCode="AU" term="%22Campbell+T%22">Campbell T</searchLink>; Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; College of Medicine, University of Cincinnati, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Slone+J%22">Slone J</searchLink>; Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; College of Medicine, University of Cincinnati, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Vu+J%22">Vu J</searchLink>; Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22Liu+W%22">Liu W</searchLink>; Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22Yang+L%22">Yang L</searchLink>; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, Xiangya Hospital; Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Dourson+A%22">Dourson A</searchLink>; Department of Anesthesia, Division of Pain Management, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Queme+LF%22">Queme LF</searchLink>; Department of Anesthesia, Division of Pain Management, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Biomedical Sciences, University of New England College of Osteopathic Medicine, Biddeford, ME, USA.<br /><searchLink fieldCode="AU" term="%22Jankowski+MP%22">Jankowski MP</searchLink>; College of Medicine, University of Cincinnati, Cincinnati, OH, USA.; Department of Anesthesia, Division of Pain Management, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Huang+T%22">Huang T</searchLink>; Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA. taosheng.huang@gmail.com.; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. taosheng.huang@gmail.com.; College of Medicine, University of Cincinnati, Cincinnati, OH, USA. taosheng.huang@gmail.com.; Institute of Medical Genetics & Genomics, Fudan University, 1st Floor, Building B, Suite 1027, Research Building 2, No. 131 Dong'an Road, Xuhui District, Shanghai, China. taosheng.huang@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%22101665035%22">Cell death discovery</searchLink> [Cell Death Discov] 2025 Dec 23; Vol. 11 (1), pp. 563. <i>Date of Electronic Publication: </i>2025 Dec 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101665035 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2058-7716 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220587716%22">20587716 </searchLink><i>NLM ISO Abbreviation: </i>Cell Death Discov <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2025 Dec 23
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