Human fibrosarcoma cells selected for ultra-high doxorubicin resistance, acquire trabectedin cross-resistance, remain sensitive to recombinant methioninase, and have increased c-MYC expression.
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| Title: | Human fibrosarcoma cells selected for ultra-high doxorubicin resistance, acquire trabectedin cross-resistance, remain sensitive to recombinant methioninase, and have increased c-MYC expression. |
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| Authors: | Morinaga S; AntiCancer Inc., San Diego, CA, United States.; Department of Surgery, University of California, San Diego, San Diego, CA, United States.; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Han Q; AntiCancer Inc., San Diego, CA, United States., Mizuta K; AntiCancer Inc., San Diego, CA, United States.; Department of Surgery, University of California, San Diego, San Diego, CA, United States., Kang BM; AntiCancer Inc., San Diego, CA, United States.; Department of Surgery, University of California, San Diego, San Diego, CA, United States., Bouvet M; Department of Surgery, University of California, San Diego, San Diego, CA, United States., Yamamoto N; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Hayashi K; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Kimura H; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Miwa S; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Igarashi K; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Higuchi T; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Tsuchiya H; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Demura S; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Hoffman RM; AntiCancer Inc., San Diego, CA, United States.; Department of Surgery, University of California, San Diego, San Diego, CA, United States. |
| Source: | Frontiers in oncology [Front Oncol] 2025 Dec 08; Vol. 15, pp. 1704021. Date of Electronic Publication: 2025 Dec 08 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2234-943X |
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| DOI: | 10.3389/fonc.2025.1704021 |
