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Human fibrosarcoma cells selected for ultra-high doxorubicin resistance, acquire trabectedin cross-resistance, remain sensitive to recombinant methioninase, and have increased c-MYC expression.

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Title: Human fibrosarcoma cells selected for ultra-high doxorubicin resistance, acquire trabectedin cross-resistance, remain sensitive to recombinant methioninase, and have increased c-MYC expression.
Authors: Morinaga S; AntiCancer Inc., San Diego, CA, United States.; Department of Surgery, University of California, San Diego, San Diego, CA, United States.; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Han Q; AntiCancer Inc., San Diego, CA, United States., Mizuta K; AntiCancer Inc., San Diego, CA, United States.; Department of Surgery, University of California, San Diego, San Diego, CA, United States., Kang BM; AntiCancer Inc., San Diego, CA, United States.; Department of Surgery, University of California, San Diego, San Diego, CA, United States., Bouvet M; Department of Surgery, University of California, San Diego, San Diego, CA, United States., Yamamoto N; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Hayashi K; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Kimura H; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Miwa S; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Igarashi K; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Higuchi T; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Tsuchiya H; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Demura S; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan., Hoffman RM; AntiCancer Inc., San Diego, CA, United States.; Department of Surgery, University of California, San Diego, San Diego, CA, United States.
Source: Frontiers in oncology [Front Oncol] 2025 Dec 08; Vol. 15, pp. 1704021. Date of Electronic Publication: 2025 Dec 08 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Human fibrosarcoma cells selected for ultra-high doxorubicin resistance, acquire trabectedin cross-resistance, remain sensitive to recombinant methioninase, and have increased c-MYC expression.
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  Data: <searchLink fieldCode="AU" term="%22Morinaga+S%22">Morinaga S</searchLink>; AntiCancer Inc., San Diego, CA, United States.; Department of Surgery, University of California, San Diego, San Diego, CA, United States.; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Han+Q%22">Han Q</searchLink>; AntiCancer Inc., San Diego, CA, United States.<br /><searchLink fieldCode="AU" term="%22Mizuta+K%22">Mizuta K</searchLink>; AntiCancer Inc., San Diego, CA, United States.; Department of Surgery, University of California, San Diego, San Diego, CA, United States.<br /><searchLink fieldCode="AU" term="%22Kang+BM%22">Kang BM</searchLink>; AntiCancer Inc., San Diego, CA, United States.; Department of Surgery, University of California, San Diego, San Diego, CA, United States.<br /><searchLink fieldCode="AU" term="%22Bouvet+M%22">Bouvet M</searchLink>; Department of Surgery, University of California, San Diego, San Diego, CA, United States.<br /><searchLink fieldCode="AU" term="%22Yamamoto+N%22">Yamamoto N</searchLink>; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Hayashi+K%22">Hayashi K</searchLink>; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Kimura+H%22">Kimura H</searchLink>; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Miwa+S%22">Miwa S</searchLink>; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Igarashi+K%22">Igarashi K</searchLink>; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Higuchi+T%22">Higuchi T</searchLink>; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Tsuchiya+H%22">Tsuchiya H</searchLink>; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Demura+S%22">Demura S</searchLink>; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Hoffman+RM%22">Hoffman RM</searchLink>; AntiCancer Inc., San Diego, CA, United States.; Department of Surgery, University of California, San Diego, San Diego, CA, United States.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101568867 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2234-943X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222234943X%22">2234943X </searchLink><i>NLM ISO Abbreviation: </i>Front Oncol <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2025 Dec 08
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