Ephrin-A1/EphA2 modulates vascular smooth muscle cell proliferation in vitro, while VSMC-specific ephrin-A1 deletion is not sufficient to alter arteriosclerosis in vivo.

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Title: Ephrin-A1/EphA2 modulates vascular smooth muscle cell proliferation in vitro, while VSMC-specific ephrin-A1 deletion is not sufficient to alter arteriosclerosis in vivo.
Authors: Augstein A; Department of Internal Medicine and Cardiology, Laboratory of Experimental and Molecular Cardiology, Heart Center Dresden, Faculty of Medicine and University Hospital, TU Dresden, Fetscherstr. 76, 01307 Dresden, Germany. Electronic address: antje.augstein@tu-dresden.de., Porth S; Department of Internal Medicine and Cardiology, Laboratory of Experimental and Molecular Cardiology, Heart Center Dresden, Faculty of Medicine and University Hospital, TU Dresden, Fetscherstr. 76, 01307 Dresden, Germany., Mierke J; Department of Internal Medicine and Cardiology, Laboratory of Experimental and Molecular Cardiology, Heart Center Dresden, Faculty of Medicine and University Hospital, TU Dresden, Fetscherstr. 76, 01307 Dresden, Germany., Friedrich J; Department of Internal Medicine and Cardiology, Laboratory of Experimental and Molecular Cardiology, Heart Center Dresden, Faculty of Medicine and University Hospital, TU Dresden, Fetscherstr. 76, 01307 Dresden, Germany., Jellinghaus S; Department of Internal Medicine and Cardiology, Laboratory of Experimental and Molecular Cardiology, Heart Center Dresden, Faculty of Medicine and University Hospital, TU Dresden, Fetscherstr. 76, 01307 Dresden, Germany., Linke A; Department of Internal Medicine and Cardiology, Laboratory of Experimental and Molecular Cardiology, Heart Center Dresden, Faculty of Medicine and University Hospital, TU Dresden, Fetscherstr. 76, 01307 Dresden, Germany., Adams V; Department of Internal Medicine and Cardiology, Laboratory of Experimental and Molecular Cardiology, Heart Center Dresden, Faculty of Medicine and University Hospital, TU Dresden, Fetscherstr. 76, 01307 Dresden, Germany., Poitz DM; Department of Internal Medicine and Cardiology, Laboratory of Experimental and Molecular Cardiology, Heart Center Dresden, Faculty of Medicine and University Hospital, TU Dresden, Fetscherstr. 76, 01307 Dresden, Germany.
Source: Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2026 Feb; Vol. 1873 (2), pp. 120098. Date of Electronic Publication: 2025 Dec 22.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731731 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2596 (Electronic) Linking ISSN: 01674889 NLM ISO Abbreviation: Biochim Biophys Acta Mol Cell Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1879-2596
DOI:10.1016/j.bbamcr.2025.120098