Genetic and environmental effects on weight gain from young adulthood to old age and its association with body mass index in early young adulthood: an individual-based pooled analysis of 16 twin cohorts.

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Title: Genetic and environmental effects on weight gain from young adulthood to old age and its association with body mass index in early young adulthood: an individual-based pooled analysis of 16 twin cohorts.
Authors: Obeso A; Helsinki Institute for Demography and Population Health, University of Helsinki, Helsinki, Finland. alvaro.obeso@helsinki.fi.; Department of Genetics, Physical Anthropology and Animal Physiology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Bilbao, Spain. alvaro.obeso@helsinki.fi., Drouard G; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland., Jelenkovic A; Department of Genetics, Physical Anthropology and Animal Physiology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Bilbao, Spain., Ordoñana JR; Department of Human Anatomy and Psychobiology, University of Murcia, Murcia, Spain., Sánchez-Romera JF; Department of Human Anatomy and Psychobiology, University of Murcia, Murcia, Spain., Colodro-Conde L; Department of Human Anatomy and Psychobiology, University of Murcia, Murcia, Spain.; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.; School of Psychology, The University of Queensland, Brisbane, QLD, Australia., Ollikainen M; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Aaltonen S; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland., Corley RP; Institute for Behavioral Genetics, University of Colorado, Boulder, CO, USA., Huibregtse BM; University of Colorado, Department of Psychology and Neuroscience, Boulder, CO, USA., Medda E; Centre for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità, Rome, Italy., Fagnani C; Centre for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità, Rome, Italy., Toccaceli V; Centre for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità, Rome, Italy., Gatz M; Center for Economic and Social Research, University of Southern California, Los Angeles, CA, USA., Butler DA; Health and Medicine Division, The National Academies of Sciences, Engineering and Medicine, Washington, DC, USA., Bartels M; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Ligthart L; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., de Geus EJ; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Christensen K; Institute of Public Health, Epidemiology, Biostatistics & Biodemography, University of Southern Denmark, Odense, Denmark., Skytthe A; Institute of Public Health, Epidemiology, Biostatistics & Biodemography, University of Southern Denmark, Odense, Denmark., Kyvik KO; Research Unit of Clinical Genetics, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark., Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Gordon SD; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Rasmussen FE; Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden., Tynelius P; Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden., Franz CE; Department of Psychiatry, University of California, San Diego, CA, USA., Kremen WS; Department of Psychiatry, University of California, San Diego, CA, USA., Lyons MJ; Department of Psychological and Brain Sciences, Boston University, Boston, MA, USA., Spector T; Department of Twin Research and Genetic epidemiology, King's College, London, UK., Mangino M; Department of Twin Research and Genetic epidemiology, King's College, London, UK., Lachance G; Department of Twin Research and Genetic epidemiology, King's College, London, UK., Magnusson PK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Dahl Aslan AK; School of Health Sciences, University of Skövde, Skövde, Sweden., Duncan GE; Washington State Twin Registry, Washington State University - Health Sciences Spokane, Spokane, WA, USA., Buchwald D; Washington State Twin Registry, University of Washington, Seattle, WA, USA., Pyun H; Department of Epidemiology, Seoul National University School of Public Health, Seoul, Korea., Lee J; Institute of Health & Environmental, Seoul National University, Seoul, Korea., Lee SJ; Institute of Health & Environmental, Seoul National University, Seoul, Korea., Sung J; Department of Epidemiology, Seoul National University School of Public Health, Seoul, Korea.; Institute of Health & Environmental, Seoul National University, Seoul, Korea., Bruins S; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Pool R; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Eriksson A; cGEM, Institute of Genomics, University of Tartu, Tartu, Estonia., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Boomsma DI; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.; Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Kaprio J; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland., Silventoinen K; Helsinki Institute for Demography and Population Health, University of Helsinki, Helsinki, Finland.
Source: International journal of obesity (2005) [Int J Obes (Lond)] 2026 Apr; Vol. 50 (4), pp. 768-776. Date of Electronic Publication: 2025 Dec 25.
Publication Type: Journal Article; Twin Study; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101256108 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5497 (Electronic) Linking ISSN: 03070565 NLM ISO Abbreviation: Int J Obes (Lond) Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5497
DOI:10.1038/s41366-025-01998-w