Antibody concentration and function following SARS-CoV-2 vaccination decrease with age in adults and children with Down syndrome.

Saved in:
Bibliographic Details
Title: Antibody concentration and function following SARS-CoV-2 vaccination decrease with age in adults and children with Down syndrome.
Authors: Streng BMM; Department of Paediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, the Netherlands., Hensen LCM; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands., Delemarre EM; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands., Binnendijk RS; Center for Immunology of Infectious Diseases and vaccines, National Institute of Public Health and the Environment, Bilthoven, the Netherlands., Smits G; Center for Immunology of Infectious Diseases and vaccines, National Institute of Public Health and the Environment, Bilthoven, the Netherlands., den Hartog G; Center for Immunology of Infectious Diseases and vaccines, National Institute of Public Health and the Environment, Bilthoven, the Netherlands; Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, the Netherlands., van der Klis FR; Center for Immunology of Infectious Diseases and vaccines, National Institute of Public Health and the Environment, Bilthoven, the Netherlands., de Vries E; Tranzo, Tilburg School of Social and Behavioral Sciences, Tilburg University, Tilburg, the Netherlands; Jeroen Bosch Academy Research, Jeroen Bosch Hospital, 's-Hertogenbosch, the Netherlands., Burger JA; Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Institute for Immunology and Infectious diseases, Amsterdam University Medical Center, Amsterdam, the Netherlands., van Gils MJ; Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Institute for Immunology and Infectious diseases, Amsterdam University Medical Center, Amsterdam, the Netherlands., Coppus AMW; Department for Primary and Community Care, Radboud University Medical Center, Nijmegen, the Netherlands., Weijerman ME; Department of Pediatrics, Alrijne Hospital, Leiderdorp, the Netherlands., Lamberts R; Foundation 'Stichting Down Syndroom', Meppel, the Netherlands., de Graaf G; Foundation 'Stichting Down Syndroom', Meppel, the Netherlands., Bont LJ; Department of Paediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, the Netherlands., Wildenbeest JG; Department of Paediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, the Netherlands. Electronic address: J.G.wildenbeest@umcutrecht.nl.
Source: Vaccine [Vaccine] 2026 Feb 15; Vol. 73, pp. 128079. Date of Electronic Publication: 2025 Dec 24.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8406899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2518 (Electronic) Linking ISSN: 0264410X NLM ISO Abbreviation: Vaccine Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-2518
DOI:10.1016/j.vaccine.2025.128079