PRR enhances anti-tumor immunity and suppresses colitis by promoting the development and survival of naive T and iNKT cells.

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Title: PRR enhances anti-tumor immunity and suppresses colitis by promoting the development and survival of naive T and iNKT cells.
Authors: Shimba A; Laboratory of Immune Regulation, Department of Virus Research, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.; Division of Integrated High-Order Regulatory Systems, Center for Cancer Immunotherapy and Immunobiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Munakata S; Laboratory of Immune Regulation, Department of Virus Research, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan., Abe S; Department of Homeostatic Medicine, Medical Research Laboratory, Institute for Integrated Research, Institute of Science Tokyo, Tokyo, Japan., Cui G; Laboratory of Immune Regulation, Department of Virus Research, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.; Jiangsu Key Laboratory of Tissue Engineering and Neuroregeneration, Key Laboratory of Neuroregeneration of Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, China., Kato R; Division of Integrated High-Order Regulatory Systems, Center for Cancer Immunotherapy and Immunobiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Miyazaki M; Laboratory of Immunology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan., Ichihara A; Department of Endocrinology and Hypertension, Tokyo Women's Medical University, Tokyo, Japan., Ikuta K; Laboratory of Immune Regulation, Department of Virus Research, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Source: Frontiers in immunology [Front Immunol] 2025 Dec 10; Vol. 16, pp. 1566935. Date of Electronic Publication: 2025 Dec 10 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1566935