Talin1 modulates the Piezo1-YAP axis to regulate endothelial cell inflammation and atherosclerosis.

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Title: Talin1 modulates the Piezo1-YAP axis to regulate endothelial cell inflammation and atherosclerosis.
Authors: Wang Y; Department of Cardiovascular Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou City, Sichuan Province, China., Huang H; Department of Cardiovascular Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou City, Sichuan Province, China., Liu Z; Department of Cardiovascular Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou City, Sichuan Province, China., Gao Z; Department of Cardiovascular Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou City, Sichuan Province, China., Liao B; Department of Cardiovascular Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou City, Sichuan Province, China.; Key Laboratory of Cardiovascular Remodeling and Dysfunction, Luzhou, China.; Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, Luzhou City, Sichuan Province, China.; Metabolic Vascular Disease Key Laboratory of Sichuan Province, Luzhou, China., Long Y; Metabolic Vascular Disease Key Laboratory of Sichuan Province, Luzhou, China.; Department of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Luzhou, China.; Sichuan Clinical Research Center for Nephropathy, Luzhou, China., Yu F; Department of Cardiovascular Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou City, Sichuan Province, China. yuluchuan@163.com.; Key Laboratory of Cardiovascular Remodeling and Dysfunction, Luzhou, China. yuluchuan@163.com.; Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, Luzhou City, Sichuan Province, China. yuluchuan@163.com.; Metabolic Vascular Disease Key Laboratory of Sichuan Province, Luzhou, China. yuluchuan@163.com., Nie Y; Department of Cardiovascular Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou City, Sichuan Province, China. nieyongmei@126.com.; Key Laboratory of Cardiovascular Remodeling and Dysfunction, Luzhou, China. nieyongmei@126.com.; Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, Luzhou City, Sichuan Province, China. nieyongmei@126.com.; Metabolic Vascular Disease Key Laboratory of Sichuan Province, Luzhou, China. nieyongmei@126.com.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2025 Dec 26; Vol. 83 (1), pp. 40. Date of Electronic Publication: 2025 Dec 26.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1420-9071
DOI:10.1007/s00018-025-06026-8