Engineered cationic Interleukin-1 receptor antagonist outperforms anakinra at joint retention and preventing IL-1-induced cartilage inflammation.

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Bibliographic Details
Title: Engineered cationic Interleukin-1 receptor antagonist outperforms anakinra at joint retention and preventing IL-1-induced cartilage inflammation.
Authors: Boyer TL; Department of Bioengineering, Northeastern University, Boston, MA, United States. Electronic address: boyer.t@northeastern.edu., Hakim B; Department of Bioengineering, Northeastern University, Boston, MA, United States. Electronic address: hakim.bi@northeastern.edu., Childress L; Graduate Program for Interdisciplinary Biomedical Sciences, UAMS, Little Rock, AR, United States. Electronic address: lchildress@uams.edu., Baby HM; Department of Bioengineering, Northeastern University, Boston, MA, United States. Electronic address: baby.h@northeastern.edu., Porter RM; Department of Internal Medicine, UAMS, Little Rock, AR, United States; Dept. of Orthopaedic Surgery, UAMS, Little Rock, AR, United States. Electronic address: rmporter@uams.edu., Bajpayee AG; Department of Bioengineering, Northeastern University, Boston, MA, United States. Electronic address: a.bajpayee@northeastern.edu.
Source: Osteoarthritis and cartilage [Osteoarthritis Cartilage] 2026 Apr; Vol. 34 (4), pp. 563-574. Date of Electronic Publication: 2025 Dec 24.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: W.B. Saunders For The Osteoarthritis Research Society Country of Publication: England NLM ID: 9305697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-9653 (Electronic) Linking ISSN: 10634584 NLM ISO Abbreviation: Osteoarthritis Cartilage Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1522-9653
DOI:10.1016/j.joca.2025.12.018