Photocontrolled trimethoprim PROTACs targeting the eDHFR protein tag.
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| Title: | Photocontrolled trimethoprim PROTACs targeting the eDHFR protein tag. |
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| Authors: | Sharma N; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Sarkar S; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Ko T; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA., Edwards KJ; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Pham JM; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Nguyen T; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Gong AZ; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Flores J; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA., Trauner D; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA. dtrauner@upenn.edu., Sellmyer MA; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. mark.sellmyer@pennmedicine.upenn.edu.; The Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. mark.sellmyer@pennmedicine.upenn.edu. |
| Source: | Nature communications [Nat Commun] 2025 Dec 27; Vol. 17 (1), pp. 822. Date of Electronic Publication: 2025 Dec 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-67527-5 |
