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AD16 as a novel therapeutic agent: Mechanisms and efficacy in chronic inflammatory pain management.

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Title: AD16 as a novel therapeutic agent: Mechanisms and efficacy in chronic inflammatory pain management.
Authors: Hu ZP; Jiangxi Province Key Laboratory of Pharmacology of Traditional Chinese Medicine, Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Ganzhou Key Laboratory of Neuroinflammation Research, School of Basic Medical Sciences, Gannan Medical University, Ganzhou 341000, China., Ma HJ; Jiangxi Province Key Laboratory of Pharmacology of Traditional Chinese Medicine, Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Ganzhou Key Laboratory of Neuroinflammation Research, School of Basic Medical Sciences, Gannan Medical University, Ganzhou 341000, China., Liu H; The First Clinical Medical College of Gannan Medical University, Ganzhou 341000, China., He ZX; The First Clinical Medical College of Gannan Medical University, Ganzhou 341000, China., Jia DD; Jiangxi Province Key Laboratory of Pharmacology of Traditional Chinese Medicine, Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Ganzhou Key Laboratory of Neuroinflammation Research, School of Basic Medical Sciences, Gannan Medical University, Ganzhou 341000, China., Sun YL; Jiangxi Province Key Laboratory of Pharmacology of Traditional Chinese Medicine, Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Ganzhou Key Laboratory of Neuroinflammation Research, School of Basic Medical Sciences, Gannan Medical University, Ganzhou 341000, China., Huang ZH; Jiangxi Province Key Laboratory of Pharmacology of Traditional Chinese Medicine, Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Ganzhou Key Laboratory of Neuroinflammation Research, School of Basic Medical Sciences, Gannan Medical University, Ganzhou 341000, China., Yuan ZD; Jiangxi Province Key Laboratory of Pharmacology of Traditional Chinese Medicine, Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Ganzhou Key Laboratory of Neuroinflammation Research, School of Basic Medical Sciences, Gannan Medical University, Ganzhou 341000, China. Electronic address: yuanzhidong@gmu.edu.cn., Chen T; Jiangxi Province Key Laboratory of Pharmacology of Traditional Chinese Medicine, Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Ganzhou Key Laboratory of Neuroinflammation Research, School of Basic Medical Sciences, Gannan Medical University, Ganzhou 341000, China. Electronic address: tchen9008@gmu.edu.cn., Huang C; Jiangxi Province Key Laboratory of Pharmacology of Traditional Chinese Medicine, Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Ganzhou Key Laboratory of Neuroinflammation Research, School of Basic Medical Sciences, Gannan Medical University, Ganzhou 341000, China; School of Basic Medical Sciences, Yichun University, Yichun 336000, China. Electronic address: huangc6a2013@gmu.edu.cn.
Source: Brain research bulletin [Brain Res Bull] 2026 Jan; Vol. 234, pp. 111707. Date of Electronic Publication: 2025 Dec 26.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605818 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2747 (Electronic) Linking ISSN: 03619230 NLM ISO Abbreviation: Brain Res Bull Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-2747
DOI:10.1016/j.brainresbull.2025.111707