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Brucella melitensis clinical isolate modulates osteoclast differentiation to drive pathological bone destruction in brucellar arthritis.

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Title: Brucella melitensis clinical isolate modulates osteoclast differentiation to drive pathological bone destruction in brucellar arthritis.
Authors: Chen J; Orthopedics Key Laboratory of Gansu Province, Department of Orthopedics, The Cuiying Biomedical Research Center, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China.; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China., Zhi F; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China., Zhao G; Orthopedics Key Laboratory of Gansu Province, Department of Orthopedics, The Cuiying Biomedical Research Center, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China., Su M; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China., Tuo J; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China., Song W; Orthopedics Key Laboratory of Gansu Province, Department of Orthopedics, The Cuiying Biomedical Research Center, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China., Chu Y; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China., Zhang H; Orthopedics Key Laboratory of Gansu Province, Department of Orthopedics, The Cuiying Biomedical Research Center, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China.
Source: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2025 Dec 12; Vol. 15, pp. 1694633. Date of Electronic Publication: 2025 Dec 12 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Brucella melitensis clinical isolate modulates osteoclast differentiation to drive pathological bone destruction in brucellar arthritis.
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  Data: <searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Orthopedics Key Laboratory of Gansu Province, Department of Orthopedics, The Cuiying Biomedical Research Center, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China.; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhi+F%22">Zhi F</searchLink>; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhao+G%22">Zhao G</searchLink>; Orthopedics Key Laboratory of Gansu Province, Department of Orthopedics, The Cuiying Biomedical Research Center, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China.<br /><searchLink fieldCode="AU" term="%22Su+M%22">Su M</searchLink>; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China.<br /><searchLink fieldCode="AU" term="%22Tuo+J%22">Tuo J</searchLink>; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China.<br /><searchLink fieldCode="AU" term="%22Song+W%22">Song W</searchLink>; Orthopedics Key Laboratory of Gansu Province, Department of Orthopedics, The Cuiying Biomedical Research Center, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China.<br /><searchLink fieldCode="AU" term="%22Chu+Y%22">Chu Y</searchLink>; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China.; Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Orthopedics Key Laboratory of Gansu Province, Department of Orthopedics, The Cuiying Biomedical Research Center, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China.
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  Data: <searchLink fieldCode="JN" term="%22101585359%22">Frontiers in cellular and infection microbiology</searchLink> [Front Cell Infect Microbiol] 2025 Dec 12; Vol. 15, pp. 1694633. <i>Date of Electronic Publication: </i>2025 Dec 12 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media+SA%22">Frontiers Media SA </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101585359 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2235-2988 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222352988%22">22352988 </searchLink><i>NLM ISO Abbreviation: </i>Front Cell Infect Microbiol <i>Subsets: </i>MEDLINE
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      – TitleFull: Brucella melitensis clinical isolate modulates osteoclast differentiation to drive pathological bone destruction in brucellar arthritis.
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              Text: 2025 Dec 12
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