Development of a CYP2D6-enhanced HepaRG cell model with improved CYP2D6 metabolic capacity.
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| Title: | Development of a CYP2D6-enhanced HepaRG cell model with improved CYP2D6 metabolic capacity. |
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| Authors: | Obara C; Stem Cells and Reprogramming Laboratory, Department of Biology, Faculty of Science, Toho University, Funabashi, Chiba, Japan., Iizaka Y; Department of Microbiology, Faculty of Pharmaceutical Sciences, Toho University, Japan., Mine A; Stem Cells and Reprogramming Laboratory, Department of Biology, Faculty of Science, Toho University, Funabashi, Chiba, Japan., Anzai Y; Department of Microbiology, Faculty of Pharmaceutical Sciences, Toho University, Japan., Tada M; Stem Cells and Reprogramming Laboratory, Department of Biology, Faculty of Science, Toho University, Funabashi, Chiba, Japan., Yamaguchi S; Stem Cells and Reprogramming Laboratory, Department of Biology, Faculty of Science, Toho University, Funabashi, Chiba, Japan. |
| Source: | PloS one [PLoS One] 2025 Dec 29; Vol. 20 (12), pp. e0339559. Date of Electronic Publication: 2025 Dec 29 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1932-6203 |
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| DOI: | 10.1371/journal.pone.0339559 |
