Dammarenediol II enhances etoposide-induced apoptosis by targeting O-GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer.

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Title: Dammarenediol II enhances etoposide-induced apoptosis by targeting O-GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer.
Authors: Lee J; R&D Headquarter Korea Ginseng Corporation, Gwacheon-si, Korea.; Cellular Reprogramming and Embryo Biotechnology Laboratory, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea., Han BC; R&D Headquarter Korea Ginseng Corporation, Gwacheon-si, Korea., Koo GB; R&D Headquarter Korea Ginseng Corporation, Gwacheon-si, Korea., Park J; R&D Headquarter Korea Ginseng Corporation, Gwacheon-si, Korea., Kwon M; R&D Headquarter Korea Ginseng Corporation, Gwacheon-si, Korea., Park YB; Calici Co., Ltd., USA, San Jose, CA, USA., Choi JM; Calici Co., Ltd., Korea, Daejeon, Korea.; Department of Bio AI Convergence, Chungnam National University, Daejeon, Korea.; Department of Food and Biotechnology, Korea University, Sejong, Korea., Lee SH; R&D Headquarter Korea Ginseng Corporation, Gwacheon-si, Korea., Roh S; Cellular Reprogramming and Embryo Biotechnology Laboratory, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea.
Source: Molecular oncology [Mol Oncol] 2026 Jun; Vol. 20 (6), pp. 1591-1611. Date of Electronic Publication: 2025 Dec 30.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1878-0261
DOI:10.1002/1878-0261.70199