Safety and efficacy of IL-23 inhibitors in patients with moderate to severe ulcerative colitis: a systematic review and meta-analysis of randomized controlled trials.

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Title: Safety and efficacy of IL-23 inhibitors in patients with moderate to severe ulcerative colitis: a systematic review and meta-analysis of randomized controlled trials.
Authors: Amin HM; Department of Internal Medicine, South Tees Hospital, Middlesbrough, UK., Hasan S; Department of Gastroenterology, University Hospitals of Leicester, Leicester, UK., Abukhater R; Department of Medicine, RAKMHSU, Ras Al Khaimah, United Arab Emirates., Lilley R; South Tyneside and Sunderland Foundation Trust, Sunderland, UK., Atique A; Department of Gastroenterology, South Warwickshire University NHS Foundation Trust, West Midlands, UK., Shoaib MS; Department of Medicine, Jinnah Sindh Medical University, Karachi, Pakistan., Albustanji Q; Department of Internal Medicine, Specialty Hospital, Amman, Jordan., Sadique H; Department of Medicine, South Tyneside and Sunderland NHS Foundation Trust, Sunderland, UK., Khalid SM; Department of Gastroenterology, The Shrewsbury and Telford Hospital NHS Trust, West Midlands, UK., Hasan A; Department of Medicine, Imperial College London, London, UK. ali.hasan21@imperial.ac.uk., Majeed S; Department of Internal Medicine, University Hospitals of Leicester, Leicester, UK., Shahzad MA; Department of Gastroenterology, Northampton General Hospital NHS Trust, Northampton, UK., Shahzad M; Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan., Ahmed M; Department of Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan., Ahmed R; National Heart & Lung Institute, Imperial College London, London, UK., Gardezi SA; Department of Gastroenterology, John's Hopkins HealthCare Aramco, Dhahran, Eastern Province, Saudi Arabia.
Source: International journal of colorectal disease [Int J Colorectal Dis] 2025 Dec 30; Vol. 41 (1), pp. 1. Date of Electronic Publication: 2025 Dec 30.
Publication Type: Journal Article; Systematic Review; Meta-Analysis
Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 8607899 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1262 (Electronic) Linking ISSN: 01791958 NLM ISO Abbreviation: Int J Colorectal Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-1262
DOI:10.1007/s00384-025-05014-5